Synthesis of a Smoothened Cholesterol: 18,19-Di-nor-cholesterol

由 Mydock-McGrane, Laurel, Rath, Nigam P., Covey, Douglas F.
出版 2014

Correction to Synthesis of a Smoothened Cholesterol: 18,19-Di-nor-cholesterol

由 Mydock-McGrane, Laurel, Rath, Nigam P., Covey, Douglas F.
發表在 J Org Chem (2015)

Rational Design Strategies for FimH Antagonists: New Drugs on the Horizon for Urinary Tract Infection and Crohn's Disease

由 Mydock-McGrane, Laurel K., Hannan, Thomas J., Janetka, James W.
發表在 Expert Opin Drug Discov (2017)

Eliminating the Roughness in Cholesterol’s β-Face: Does it Matter?

由 Krause, Martin R., Wang, Minghui, Mydock-McGrane, Laurel, Covey, Douglas F., Tejada, Emmanuel, Almeida, Paulo F., Regen, Steven L.
出版 2014

Synthesis and characterization of diazirine alkyne probes for the study of intracellular cholesterol trafficking

由 Feltes, McKenna, Moores, Samantha, Gale, Sarah E., Krishnan, Kathiresan, Mydock-McGrane, Laurel, Covey, Douglas F., Ory, Daniel S., Schaffer, Jean E.
發表在 J Lipid Res (2019)

Structure-based discovery of glycomimetic FmlH ligands as inhibitors of bacterial adhesion during urinary tract infection

由 Kalas, Vasilios, Hibbing, Michael E., Maddirala, Amarendar Reddy, Chugani, Ryan, Pinkner, Jerome S., Mydock-McGrane, Laurel K., Conover, Matt S., Janetka, James W., Hultgren, Scott J.
發表在 Proc Natl Acad Sci U S A (2018)

Side-Chain Oxysterols Modulate Cholesterol Accessibility through Membrane Remodeling

由 Bielska, Agata A., Olsen, Brett N., Gale, Sarah E., Mydock-McGrane, Laurel, Krishnan, Kathiresan, Baker, Nathan A., Schlesinger, Paul H., Covey, Douglas F., Ory, Daniel S.
出版 2014

Common binding sites for cholesterol and neurosteroids on a pentameric ligand-gated ion channel

由 Budelier, Melissa M., Cheng, Wayland W. L., Chen, Zi-Wei, Bracamontes, John R., Sugasawa, Yusuke, Kathiresan, Krishnan, Mydock-McGrane, Laurel, Covey, Douglas F., Evers, Alex S.
發表在 Biochim Biophys Acta Mol Cell Biol Lipids (2018)

Tracking the Subcellular Fate of 20(S)-Hydroxycholesterol with Click Chemistry Reveals a Transport Pathway to the Golgi

由 Peyrot, Sara M., Nachtergaele, Sigrid, Luchetti, Giovanni, Mydock-McGrane, Laurel K., Fujiwara, Hideji, Scherrer, David, Jallouk, Andrew, Schlesinger, Paul H., Ory, Daniel S., Covey, Douglas F., Rohatgi, Rajat
出版 2014

Antivirulence Isoquinolone Mannosides: Optimization of the Biaryl Aglycone for FimH Lectin Binding Affinity and Efficacy in the Treatment of Chronic UTI

由 Jarvis, Cassie, Han, Zhenfu, Kalas, Vasilios, Klein, Roger, Pinkner, Jerome S., Ford, Bradley, Binkley, Jana, Cusumano, Corinne K., Cusumano, Zachary, Mydock-McGrane, Laurel, Hultgren, Scott J., Janetka, James W.
發表在 ChemMedChem (2016)

Antivirulence C-Mannosides as Antibiotic-Sparing, Oral Therapeutics for Urinary Tract Infections

由 Mydock-McGrane, Laurel, Cusumano, Zachary, Han, Zhenfu, Binkley, Jana, Kostakioti, Maria, Hannan, Thomas, Pinkner, Jerome S., Klein, Roger, Kalas, Vasilios, Crowley, Jan, Rath, Nigam P., Hultgren, Scott J., Janetka, James W.
發表在 J Med Chem (2016)

Photoaffinity labeling with cholesterol analogues precisely maps a cholesterol-binding site in voltage-dependent anion channel-1

由 Budelier, Melissa M., Cheng, Wayland W. L., Bergdoll, Lucie, Chen, Zi-Wei, Janetka, James W., Abramson, Jeff, Krishnan, Kathiresan, Mydock-McGrane, Laurel, Covey, Douglas F., Whitelegge, Julian P., Evers, Alex S.
發表在 J Biol Chem (2017)

Structural basis for Smoothened regulation by its extracellular domains

由 Byrne, Eamon F.X., Sircar, Ria, Miller, Paul S., Hedger, George, Luchetti, Giovanni, Nachtergaele, Sigrid, Tully, Mark D., Mydock-McGrane, Laurel, Covey, Douglas F., Rambo, Robert P., Sansom, Mark S. P., Newstead, Simon, Rohatgi, Rajat, Siebold, Christian
發表在 Nature (2016)

Lysosomal Cholesterol Activates mTORC1 via an SLC38A9-Niemann Pick C1 Signaling Complex

由 Castellano, Brian M., Thelen, Ashley M., Moldavski, Ofer, Feltes, McKenna, van der Welle, Reini E. N., Mydock-McGrane, Laurel, Jiang, Xuntian, van Eijkeren, Robert J, Davis, Oliver B., Louie, Sharon M., Perera, Rushika M., Covey, Douglas, Nomura, Daniel K., Ory, Daniel S., Zoncu, Roberto
發表在 Science (2017)