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Synthesis and characterization of diazirine alkyne probes for the study of intracellular cholesterol trafficking

Cholesterol is an essential structural component of cellular membranes and precursor molecule for oxysterol, bile acid, and hormone synthesis. The study of intracellular cholesterol trafficking pathways has been limited in part due to a lack of suitable cholesterol analogues. Herein, we developed th...

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Detalhes bibliográficos
Publicado no:J Lipid Res
Main Authors: Feltes, McKenna, Moores, Samantha, Gale, Sarah E., Krishnan, Kathiresan, Mydock-McGrane, Laurel, Covey, Douglas F., Ory, Daniel S., Schaffer, Jean E.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6399506/
https://ncbi.nlm.nih.gov/pubmed/30617147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.D091470
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