Benzene Oxide is a Substrate for Glutathione S-Transferases

Por Zarth, Adam T., Murphy, Sharon E., Hecht, Stephen S.
Publicado no Chem Biol Interact (2015)

Effect of CYP2A13 Active Site Mutation N297A on Metabolism of Coumarin and Tobacco-Specific Nitrosamines

Por Schlicht, Kari E., Berg, Jeannette Zinggeler, Murphy, Sharon E.
Publicado em 2009

CYP2A6- and CYP2A13-Catalyzed Metabolism of the Nicotine Δ(5′(1′))Iminium Ion

Por von Weymarn, Linda B., Retzlaff, Cassandra, Murphy, Sharon E.
Publicado em 2012

Inhibition and inactivation of cytochrome P450 2A6 and cytochrome P450 2A13 by menthofuran, β-nicotyrine and menthol

Por Kramlinger, Valerie M., von Weymarn, Linda B., Murphy, Sharon E.
Publicado em 2012

2′-Hydroxylation of nicotine by cytochrome P450 2A6 and human liver microsomes: Formation of a lung carcinogen precursor

Por Hecht, Stephen S., Hochalter, J. Bradley, Villalta, Peter W., Murphy, Sharon E.
Publicado em 2000

Analysis of [3′,3′-d(2)]-nicotine and [3′,3′-d(2)]-cotinine by capillary liquid chromatography-electrospray tandem mass spectrometry

Por Murphy, Sharon E., Villalta, Peter, Ho, Sing-Wei, von Weymarn, Linda B.
Publicado em 2007

Combined Analysis of the Tobacco Metabolites Cotinine and 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol in Human Urine

Por Kotandeniya, Delshanee, Carmella, Steven G., Ming, Xun, Murphy, Sharon E., Hecht, Stephen S.
Publicado no Anal Chem (2014)

Tobacco Smoke Biomarkers and Cancer Risk Among Male Smokers in the Shanghai Cohort Study

Por Hecht, Stephen S., Murphy, Sharon E., Stepanov, Irina, Nelson, Heather H., Yuan, Jian-Min
Publicado em 2012

Nicotine Metabolism in African Americans and European Americans: Variation in Glucuronidation by Ethnicity and UGT2B10 Haplotype

Por Berg, Jeannette Zinggeler, Mason, Jesse, Boettcher, Angela J., Hatsukami, Dorothy K., Murphy, Sharon E.
Publicado em 2010

Cotinine and trans 3'-Hydroxycotinine in Dried Blood Spots as Biomarkers of Tobacco Exposure and Nicotine Metabolism

Por Murphy, Sharon E., Wickham, Katherine M., Lindgren, Bruce R., Spector, Logan G., Joseph, Anne
Publicado em 2013

Prenatal Tobacco Exposure and Cotinine in Newborn Dried Blood Spots

Por Spector, Logan G., Murphy, Sharon E., Wickham, Katherine M., Lindgren, Bruce, Joseph, Anne M.
Publicado em 2014

Chronic Nicotine Consumption does not Influence 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone Induced Lung Tumorigenesis

Por Murphy, Sharon E., von Weymarn, Linda B., Schutten, Melissa M., Kassie, Fekadu, Modiano, Jaime F.
Publicado em 2011

Exposure to the Carcinogen 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanone (NNK) in Smokers from Three Populations with Different Risks of Lung Cancer

Por Derby, Kiersten, Cuthrell, Kristine, Caberto, Christian, Carmella, Steven, Murphy, Sharon E., Hecht, Stephen S., Le Marchand, Loïc
Publicado em 2009

CYP2B6 Non-Coding Variation Associated with Smoking Cessation Is Also Associated with Differences in Allelic Expression, Splicing, and Nicotine Metabolism Independent of Common Ami...

Por Bloom, A. Joseph, Martinez, Maribel, Chen, Li-Shiun, Bierut, Laura J., Murphy, Sharon E., Goate, Alison
Publicado em 2013

Quantitation of the minor tobacco alkaloids nornicotine, anatabine, and anabasine in smokers’ urine by high throughput liquid chromatography mass spectrometry

Por von Weymarn, Linda B., Thomson, Nicole M., Donny, Eric C., Hatsukami, Dorothy K., Murphy, Sharon E.
Publicado no Chem Res Toxicol (2016)

Stability of the Nicotine Metabolite Ratio in Ad Libitum and Reducing Smokers

Por Mooney, Marc E., Li, Zhong-ze, Murphy, Sharon E., Pentel, Paul R., Le, Chap, Hatsukami, Dorothy K.
Publicado em 2008

Exposure to Nicotine and a Tobacco-Specific Carcinogen Increase with Duration of Use of Smokeless Tobacco

Por Hecht, Stephen S., Carmella, Steven G., Edmonds, Amanda, Murphy, Sharon E., Stepanov, Irina, Luo, Xianghua, Hatsukami, Dorothy K.
Publicado em 2008

The Contribution of Common UGT2B10 and CYP2A6 Alleles to Variation in Nicotine Glucuronidation among European Americans

Por Bloom, A. Joseph, von Weymarn, Linda B., Martinez, Maribel, Bierut, Laura J., Goate, Alison, Murphy, Sharon E.
Publicado em 2013

Effects upon in vivo nicotine metabolism reveal functional variation in FMO3 associated with cigarette consumption

Por Bloom, A. Joseph, Murphy, Sharon E., Martinez, Maribel, von Weymarn, Linda B., Bierut, Laura J., Goate, Alison
Publicado no Pharmacogenet Genomics (2013)

Association of CYP2A6 activity with lung cancer incidence in smokers: The multiethnic cohort study

Por Park, Sungshim L., Murphy, Sharon E., Wilkens, Lynne R., Stram, Daniel O., Hecht, Stephen S., Le Marchand, Loïc
Publicado no PLoS One (2017)