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Stability of the Nicotine Metabolite Ratio in Ad Libitum and Reducing Smokers
BACKGROUND: The ratio of two nicotine metabolites, cotinine (COT) and trans-3′-hydroxycotinine (3-HC), has been validated as a method of phenotyping the activity of the liver enzyme cytochrome P450 (CYP) 2A6, and thus the rate of nicotine metabolism. Our objective was to evaluate the correlates and...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2765478/ https://ncbi.nlm.nih.gov/pubmed/18559554 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-08-0242 |
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