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Stability of the Nicotine Metabolite Ratio in Smokers of Progressively Reduced Nicotine Content Cigarettes

INTRODUCTION: The nicotine metabolite ratio (NMR), the ratio of trans-3′-hydroxycotinine (3-HC) to cotinine, has been used as a biomarker of the rate of CYP2A6-mediated nicotine metabolism. While stable in smokers who maintain constant smoking consumption, since smoking has been shown to inhibit nic...

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Detalhes bibliográficos
Main Authors: St. Helen, Gideon, Jacob, Peyton, Benowitz, Neal L.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3790625/
https://ncbi.nlm.nih.gov/pubmed/23674838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ntr/ntt065
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