Preferential Glutathione Conjugation of a Reverse Diol Epoxide Compared to a Bay Region Diol Epoxide of Phenanthrene in Human Hepatocytes: Relevance to Molecular Epidemiology Studi...

Tekijä Hecht, Stephen S., Berg, Jeannette Zinggeler, Hochalter, J. Bradley
Julkaistu 2009

Analysis of phenanthrene diol epoxide mercapturic acid detoxification products in human urine: relevance to molecular epidemiology studies of glutathione S-transferase polymorphism...

Tekijä Hecht, Stephen S., Villalta, Peter W., Hochalter, J.Bradley
Julkaistu 2008

Ultra-sensitive High Resolution Mass Spectrometric Analysis of a DNA Adduct of the Carcinogen Benzo[a]pyrene in Human Lung

Tekijä Villalta, Peter W., Hochalter, J. Bradley, Hecht, Stephen S.
Julkaisussa Anal Chem (2017)

Quantitation of Phenanthrene Dihydrodiols in the Urine of Smokers and Non-smokers by Gas Chromatography-Negative Ion Chemical Ionization-Tandem Mass Spectrometry

Tekijä Luo, Kai, Hochalter, J. Bradley, Carmella, Steven G., Hecht, Stephen S.
Julkaisussa J Chromatogr B Analyt Technol Biomed Life Sci (2020)

2′-Hydroxylation of nicotine by cytochrome P450 2A6 and human liver microsomes: Formation of a lung carcinogen precursor

Tekijä Hecht, Stephen S., Hochalter, J. Bradley, Villalta, Peter W., Murphy, Sharon E.
Julkaistu 2000

Analysis of Phenanthrene and Benzo[a]pyrene Tetraol Enantiomers in Human Urine: Relevance to the Bay Region Diol Epoxide Hypothesis of Benzo[a]pyrene Carcinogenesis and to Biomarke...

Tekijä Hecht, Stephen S., Carmella, Steven G., Villalta, Peter W., Hochalter, J. Bradley
Julkaistu 2010

Quantitation of Pyridylhydroxybutyl-DNA Adducts in Liver and Lung of F-344 Rats Treated with 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone and Enantiomers of its Metabolite 4-(Met...

Tekijä Upadhyaya, Pramod, Kalscheuer, Stephen, Hochalter, J. Bradley, Villalta, Peter W., Hecht, Stephen S.
Julkaistu 2008

Quantitation of a Minor Enantiomer of Phenanthrene Tetraol in Human Urine: Correlations with Levels of Overall Phenanthrene Tetraol, Benzo[a]pyrene Tetraol, and 1-Hydroxypyrene

Tekijä Hochalter, J. Bradley, Zhong, Yan, Han, Shaomei, Carmella, Steven G., Hecht, Stephen S.
Julkaistu 2011

Analysis of r-7,t-8,9,c-10-Tetrahydroxy-7,8,9,10-tetrahydrobenzo[a]pyrene in Human Urine: A Biomarker for Directly Assessing Carcinogenic Polycyclic Aromatic Hydrocarbon Exposure p...

Tekijä Zhong, Yan, Carmella, Steven G., Hochalter, J. Bradley, Balbo, Silvia, Hecht, Stephen S.
Julkaistu 2010

Methyl DNA phosphate adduct formation in lung tumor tissue and adjacent normal tissue of lung cancer patients

Tekijä Ma, Bin, Villalta, Peter W, Hochalter, J Bradley, Stepanov, Irina, Hecht, Stephen S
Julkaisussa Carcinogenesis (2019)

Preferential Glutathione Conjugation of a Reverse Diol Epoxide Compared with a Bay Region Diol Epoxide of Benzo[a]pyrene in Human Hepatocytes

Tekijä Upadhyaya, Pramod, Hochalter, J. Bradley, Balbo, Silvia, McIntee, Edward J., Hecht, Stephen S.
Julkaistu 2010

Identification of an Acetaldehyde Adduct in Human Liver DNA and Quantitation as N(2)-Ethyldeoxyguanosine

Tekijä Wang, Mingyao, Yu, Nanxiong, Chen, Li, Villalta, Peter W., Hochalter, J. Bradley, Hecht, Stephen S.
Julkaistu 2006

Quantitation of N-Acetyl-S-(9,10-dihydro-9-hydroxy-10-phenanthryl)-L-cysteine in Human Urine: Comparison with Glutathione-S-transferase Genotypes in Smokers

Tekijä Upadhyaya, Pramod, Rao, Priyanka, Hochalter, J. Bradley, Li, Zhong-ze, Villalta, Peter W., Hecht, Stephen S.
Julkaistu 2006

Longitudinal Study of [D(10)]Phenanthrene Metabolism by the Diol Epoxide Pathway in Smokers

Tekijä Hecht, Stephen S., Hochalter, J. Bradley, Carmella, Steven G., Zhang, Yan, Rauch, Diane M., Fujioka, Naomi, Jensen, Joni, Hatsukami, Dorothy K.
Julkaistu 2013

Investigation of the Reaction of Myosmine with Sodium Nitrite in vitro and in Rats

Tekijä Hecht, Stephen S., Han, Shaomei, Kenney, Patrick M.J., Wang, Mingyao, Lindgren, Bruce, Wang, Yong, Lao, Yanbin, Hochalter, J. Bradley, Upadhyaya, Pramod
Julkaistu 2007

Immediate Consequences of Cigarette Smoking: Rapid Formation of Polycyclic Aromatic Hydrocarbon Diol Epoxides

Tekijä Zhong, Yan, Carmella, Steven G., Upadhyaya, Pramod, Hochalter, J. Bradley, Rauch, Diane, Oliver, Andrew, Jensen, Joni, Hatsukami, Dorothy, Wang, Jing, Zimmerman, Cheryl, Hecht, Stephen S.
Julkaistu 2010

Metabolism of [D(10)]Phenanthrene to Tetraols in Smokers for Potential Lung Cancer Susceptibility Assessment: Comparison of Oral and Inhalation Routes of Administration

Tekijä Zhong, Yan, Wang, Jing, Carmella, Steven G., Hochalter, J. Bradley, Rauch, Diane, Oliver, Andrew, Jensen, Joni, Hatsukami, Dorothy K., Upadhyaya, Pramod, Zimmerman, Cheryl, Hecht, Stephen S.
Julkaistu 2011

Phenanthrene Metabolism in Smokers: Use of a Two-Step Diagnostic Plot Approach to Identify Subjects with Extensive Metabolic Activation

Tekijä Wang, Jing, Zhong, Yan, Carmella, Steven G., Hochalter, J. Bradley, Rauch, Diane, Oliver, Andrew, Jensen, Joni, Hatsukami, Dorothy K., Upadhyaya, Pramod, Hecht, Stephen S., Zimmerman, Cheryl L.
Julkaistu 2012

Cigarette smoking enhances the metabolic activation of the polycyclic aromatic hydrocarbon phenanthrene in humans

Tekijä Luo, Kai, Luo, Xianghua, Cao, Wenhao, Hochalter, J Bradley, Paiano, Viviana, Sipe, Christopher J, Carmella, Steven G, Murphy, Sharon E, Jensen, Joni, Lam, Stephen, Golin, Andrew P, Bergstrom, Lori, Midthun, David, Fujioka, Naomi, Hatsukami, Dorothy, Hecht, Stephen S
Julkaisussa Carcinogenesis (2020)