Preferential Glutathione Conjugation of a Reverse Diol Epoxide Compared to a Bay Region Diol Epoxide of Phenanthrene in Human Hepatocytes: Relevance to Molecular Epidemiology Studi...

Por Hecht, Stephen S., Berg, Jeannette Zinggeler, Hochalter, J. Bradley
Publicado em 2009

Analysis of phenanthrene diol epoxide mercapturic acid detoxification products in human urine: relevance to molecular epidemiology studies of glutathione S-transferase polymorphism...

Por Hecht, Stephen S., Villalta, Peter W., Hochalter, J.Bradley
Publicado em 2008

2′-Hydroxylation of nicotine by cytochrome P450 2A6 and human liver microsomes: Formation of a lung carcinogen precursor

Por Hecht, Stephen S., Hochalter, J. Bradley, Villalta, Peter W., Murphy, Sharon E.
Publicado em 2000

Analysis of Phenanthrene and Benzo[a]pyrene Tetraol Enantiomers in Human Urine: Relevance to the Bay Region Diol Epoxide Hypothesis of Benzo[a]pyrene Carcinogenesis and to Biomarke...

Por Hecht, Stephen S., Carmella, Steven G., Villalta, Peter W., Hochalter, J. Bradley
Publicado em 2010

Quantitation of Pyridylhydroxybutyl-DNA Adducts in Liver and Lung of F-344 Rats Treated with 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone and Enantiomers of its Metabolite 4-(Met...

Por Upadhyaya, Pramod, Kalscheuer, Stephen, Hochalter, J. Bradley, Villalta, Peter W., Hecht, Stephen S.
Publicado em 2008

Quantitation of a Minor Enantiomer of Phenanthrene Tetraol in Human Urine: Correlations with Levels of Overall Phenanthrene Tetraol, Benzo[a]pyrene Tetraol, and 1-Hydroxypyrene

Por Hochalter, J. Bradley, Zhong, Yan, Han, Shaomei, Carmella, Steven G., Hecht, Stephen S.
Publicado em 2011

Analysis of r-7,t-8,9,c-10-Tetrahydroxy-7,8,9,10-tetrahydrobenzo[a]pyrene in Human Urine: A Biomarker for Directly Assessing Carcinogenic Polycyclic Aromatic Hydrocarbon Exposure p...

Por Zhong, Yan, Carmella, Steven G., Hochalter, J. Bradley, Balbo, Silvia, Hecht, Stephen S.
Publicado em 2010

Preferential Glutathione Conjugation of a Reverse Diol Epoxide Compared with a Bay Region Diol Epoxide of Benzo[a]pyrene in Human Hepatocytes

Por Upadhyaya, Pramod, Hochalter, J. Bradley, Balbo, Silvia, McIntee, Edward J., Hecht, Stephen S.
Publicado em 2010

Identification of an Acetaldehyde Adduct in Human Liver DNA and Quantitation as N(2)-Ethyldeoxyguanosine

Por Wang, Mingyao, Yu, Nanxiong, Chen, Li, Villalta, Peter W., Hochalter, J. Bradley, Hecht, Stephen S.
Publicado em 2006

Quantitation of N-Acetyl-S-(9,10-dihydro-9-hydroxy-10-phenanthryl)-L-cysteine in Human Urine: Comparison with Glutathione-S-transferase Genotypes in Smokers

Por Upadhyaya, Pramod, Rao, Priyanka, Hochalter, J. Bradley, Li, Zhong-ze, Villalta, Peter W., Hecht, Stephen S.
Publicado em 2006

Longitudinal Study of [D(10)]Phenanthrene Metabolism by the Diol Epoxide Pathway in Smokers

Por Hecht, Stephen S., Hochalter, J. Bradley, Carmella, Steven G., Zhang, Yan, Rauch, Diane M., Fujioka, Naomi, Jensen, Joni, Hatsukami, Dorothy K.
Publicado em 2013

Investigation of the Reaction of Myosmine with Sodium Nitrite in vitro and in Rats

Por Hecht, Stephen S., Han, Shaomei, Kenney, Patrick M.J., Wang, Mingyao, Lindgren, Bruce, Wang, Yong, Lao, Yanbin, Hochalter, J. Bradley, Upadhyaya, Pramod
Publicado em 2007

Immediate Consequences of Cigarette Smoking: Rapid Formation of Polycyclic Aromatic Hydrocarbon Diol Epoxides

Por Zhong, Yan, Carmella, Steven G., Upadhyaya, Pramod, Hochalter, J. Bradley, Rauch, Diane, Oliver, Andrew, Jensen, Joni, Hatsukami, Dorothy, Wang, Jing, Zimmerman, Cheryl, Hecht, Stephen S.
Publicado em 2010

Metabolism of [D(10)]Phenanthrene to Tetraols in Smokers for Potential Lung Cancer Susceptibility Assessment: Comparison of Oral and Inhalation Routes of Administration

Por Zhong, Yan, Wang, Jing, Carmella, Steven G., Hochalter, J. Bradley, Rauch, Diane, Oliver, Andrew, Jensen, Joni, Hatsukami, Dorothy K., Upadhyaya, Pramod, Zimmerman, Cheryl, Hecht, Stephen S.
Publicado em 2011

Phenanthrene Metabolism in Smokers: Use of a Two-Step Diagnostic Plot Approach to Identify Subjects with Extensive Metabolic Activation

Por Wang, Jing, Zhong, Yan, Carmella, Steven G., Hochalter, J. Bradley, Rauch, Diane, Oliver, Andrew, Jensen, Joni, Hatsukami, Dorothy K., Upadhyaya, Pramod, Hecht, Stephen S., Zimmerman, Cheryl L.
Publicado em 2012