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Identification of an Acetaldehyde Adduct in Human Liver DNA and Quantitation as N(2)-Ethyldeoxyguanosine

Acetaldehyde, a ubiquitous mutagen and carcinogen, could be involved in human cancer etiology. Since DNA adducts are important in carcinogenesis, we have used liquid chromatography-electrospray ionization-tandem mass spectrometry (LC-ESI-MS/MS) to explore the presence in human liver DNA of the major...

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Main Authors: Wang, Mingyao, Yu, Nanxiong, Chen, Li, Villalta, Peter W., Hochalter, J. Bradley, Hecht, Stephen S.
Formato: Artigo
Idioma:Inglês
Publicado: 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3199962/
https://ncbi.nlm.nih.gov/pubmed/16485909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx0502948
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