Smoking and lung cancer—a new role for an old toxicant?

Por Hecht, Stephen S.
Publicado em 2006

Progress and Challenges in Selected Areas of Tobacco Carcinogenesis

Por Hecht, Stephen S.
Publicado em 2007

Research Opportunities Related to Establishing Standards for Tobacco Products Under the Family Smoking Prevention and Tobacco Control Act

Por Hecht, Stephen S.
Publicado em 2012

Lung Carcinogenesis by Tobacco Smoke

Por Hecht, Stephen S.
Publicado em 2012

It is time to regulate carcinogenic tobacco-specific nitrosamines in cigarette tobacco

Por Hecht, Stephen S.
Publicado em 2014

Oral Cell DNA Adducts as Potential Biomarkers for Lung Cancer Susceptibility in Cigarette Smokers

Por Hecht, Stephen S.
Publicado no Chem Res Toxicol (2016)

Identification of Adducts Formed in the Reactions of 5′-Acetoxy-N′-nitrosonornicotine with Deoxyadenosine, Thymidine, and DNA

Por Upadhyaya, Pramod, Hecht, Stephen S.
Publicado em 2008

Mitochondrial DNA adducts in the lung and liver of F344 rats chronically treated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and (S)-4-(methylnitrosamino)-1-(3-pyridyl)-1-b...

Por Stepanov, Irina, Hecht, Stephen S.
Publicado em 2009

Detection and Quantitation of N′-Nitrosonornicotine in Human Toenails by Liquid Chromatography-Electrospray Ionization-Tandem Mass Spectrometry

Por Stepanov, Irina, Hecht, Stephen S.
Publicado em 2008

Fifty Years of Tobacco Carcinogenesis Research: From Mechanisms to Early Detection and Prevention of Lung Cancer

Por Hecht, Stephen S., Szabo, Eva
Publicado no Cancer Prev Res (Phila) (2014)

Quantitative Analysis of 3′-Hydroxynorcotinine in Human Urine

Por Upadhyaya, Pramod, Hecht, Stephen S.
Publicado no Nicotine Tob Res (2015)

Quantitation of enantiomers of r-7,t-8,9,c-10-tetrahydroxy-7,8,9,10-tetrahydrobenzo[a]-pyrene in human urine: evidence supporting metabolic activation of benzo[a]pyrene via the bay...

Por Hecht, Stephen S., Hochalter, Jon Bradley
Publicado em 2014

Evolution of Research on the DNA Adduct Chemistry of N-Nitrosopyrrolidine and Related Aldehydes

Por Hecht, Stephen S., Upadhyaya, Pramod, Wang, Mingyao
Publicado em 2011

Comparative Levels of O(6)-Methylguanine, Pyridyloxobutyl-, and Pyridylhydroxybutyl-DNA Adducts in Lung and Liver of Rats Treated Chronically with the Tobacco-Specific Carcinogen...

Por Upadhyaya, Pramod, Lindgren, Bruce R., Hecht, Stephen S.
Publicado em 2009

Applying Tobacco Carcinogen and Toxicant Biomarkers in Product Regulation and Cancer Prevention

Por Hecht, Stephen S., Yuan, Jian-Min, Hatsukami, Dorothy
Publicado em 2010

Quantitation of 7-Ethylguanine in Leukocyte DNA from Smokers and Nonsmokers by Liquid Chromatography-Nanoelectrospray-High Resolution Tandem Mass Spectrometry

Por Balbo, Silvia, Villalta, Peter W., Hecht, Stephen S.
Publicado em 2011

Major tobacco companies have technology to reduce carcinogen levels but do not apply it to popular smokeless tobacco products

Por Hecht, Stephen S., Stepanov, Irina, Hatsukami, Dorothy K.
Publicado em 2010

Chemoprevention of Lung Carcinogenesis in Addicted Smokers and Ex-Smokers

Por Hecht, Stephen S., Kassie, Fekadu, Hatsukami, Dorothy K.
Publicado em 2009

Benzene Oxide is a Substrate for Glutathione S-Transferases

Por Zarth, Adam T., Murphy, Sharon E., Hecht, Stephen S.
Publicado no Chem Biol Interact (2015)

EXPOSURE AND METABOLIC ACTIVATION BIOMARKERS OF CARCINOGENIC TOBACCO-SPECIFIC NITROSAMINES

Por Hecht, Stephen S., Stepanov, Irina, Carmella, Steven G.
Publicado no Acc Chem Res (2015)