A carregar...
Identification of Adducts Formed in the Reaction of α-Acetoxy-N-Nitrosopyrrolidine with Deoxyribonucleosides and DNA
N-Nitrosopyrrolidine (NPYR) is a well-established hepatocarcinogen in the rat. NPYR requires metabolic activation by cytochrome P450-catalyzed α-hydroxylation to express its carcinogenic activity. This produces α-hydroxyNPYR (2) which spontaneously ring opens to 4-oxobutanediazohydroxide (4), a high...
Na minha lista:
| Main Authors: | , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2518840/ https://ncbi.nlm.nih.gov/pubmed/17394360 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx600332p |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|