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Identification of Adducts Formed in the Reaction of 5′-Acetoxy-N′-Nitrosonornicotine with Deoxyguanosine and DNA

N′-Nitrosonornicotine (NNN) is believed to play an important role as a cause of cancer in people who use tobacco products and is considered to be a human carcinogen. NNN requires metabolism to form DNA adducts, which are absolutely critical to its carcinogenic properties. Previous studies have ident...

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Sonraí Bibleagrafaíochta
Main Authors: Upadhyaya, Pramod, McIntee, Edward J., Villalta, Peter W., Hecht, Stephen S.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2006
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2518848/
https://ncbi.nlm.nih.gov/pubmed/16544948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx050323e
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