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Identification of Adducts Formed in the Reaction of 5′-Acetoxy-N′-Nitrosonornicotine with Deoxyguanosine and DNA
N′-Nitrosonornicotine (NNN) is believed to play an important role as a cause of cancer in people who use tobacco products and is considered to be a human carcinogen. NNN requires metabolism to form DNA adducts, which are absolutely critical to its carcinogenic properties. Previous studies have ident...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2518848/ https://ncbi.nlm.nih.gov/pubmed/16544948 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx050323e |
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