Загрузка...
Analysis of Crotonaldehyde- and Acetaldehyde-Derived 1,N(2)-Propanodeoxyguanosine Adducts in DNA from Human Tissues using Liquid Chromatography-Electrospray Ionization-Tandem Mass Spectrometry
Crotonaldehyde, a mutagen and carcinogen, reacts with deoxyguanosine (dGuo) in DNA to generate a pair of diastereomeric 1,N(2)-propanodeoxyguanosine adducts (Cro-dGuo, 2), which occur in (6S, 8S) and (6R, 8R) configurations. They can also be formed through the consecutive reaction of two acetaldehyd...
Сохранить в:
| Главные авторы: | , , , |
|---|---|
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2006
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2596066/ https://ncbi.nlm.nih.gov/pubmed/17040109 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx060154d |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|