Immediate Consequences of Cigarette Smoking: Rapid Formation of Polycyclic Aromatic Hydrocarbon Diol Epoxides

Polycyclic aromatic hydrocarbons (PAH) are among the likely major causative agents for lung cancer in smokers. PAH require metabolic activation to exert their carcinogenic effects, and one important pathway proceeds through a three-step sequence resulting in the formation of diol epoxides which reac...

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Bibliographic Details
Main Authors: Zhong, Yan, Carmella, Steven G., Upadhyaya, Pramod, Hochalter, J. Bradley, Rauch, Diane, Oliver, Andrew, Jensen, Joni, Hatsukami, Dorothy, Wang, Jing, Zimmerman, Cheryl, Hecht, Stephen S.
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3042042/
https://ncbi.nlm.nih.gov/pubmed/21184614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx100345x
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