Preferential Glutathione Conjugation of a Reverse Diol Epoxide Compared with a Bay Region Diol Epoxide of Benzo[a]pyrene in Human Hepatocytes

Many studies have examined the relationship between polymorphisms in glutathione S-transferase genes and cancer in people exposed to polycyclic aromatic hydrocarbons (PAH) such as benzo[a]pyrene (BaP), but the results to date have been modest. Missing from these studies has been an exploration of th...

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Bibliographic Details
Main Authors: Upadhyaya, Pramod, Hochalter, J. Bradley, Balbo, Silvia, McIntee, Edward J., Hecht, Stephen S.
Format: Artigo
Language:Inglês
Published: The American Society for Pharmacology and Experimental Therapeutics 2010
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Short Communications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2939474/
https://ncbi.nlm.nih.gov/pubmed/20547966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.110.034181
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