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Analysis of phenanthrene diol epoxide mercapturic acid detoxification products in human urine: relevance to molecular epidemiology studies of glutathione S-transferase polymorphisms

Many studies have investigated the effects of glutathione S-transferase (GST) polymorphisms on cancer incidence in people exposed to carcinogenic polycyclic aromatic hydrocarbons (PAHs). The basis for this is that the carcinogenic bay region diol epoxide metabolites of several PAH are detoxified by...

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Detalhes bibliográficos
Main Authors: Hecht, Stephen S., Villalta, Peter W., Hochalter, J.Bradley
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2902377/
https://ncbi.nlm.nih.gov/pubmed/18477646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgn015
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