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The Contribution of Common UGT2B10 and CYP2A6 Alleles to Variation in Nicotine Glucuronidation among European Americans
UDP-glucuronosytransferase-2B10 (UGT2B10) is the primary catalyst of nicotine glucuronidation. To develop a predictive genetic model of nicotine metabolism, the conversion of deuterated (D(2))-nicotine to D(2)-nicotine-glucuronide, D(2)-cotinine, D(2)-cotinine-glucuronide, and D(2)-trans-3'-hyd...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3919513/ https://ncbi.nlm.nih.gov/pubmed/24192532 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0000000000000011 |
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