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Analysis of [3′,3′-d(2)]-nicotine and [3′,3′-d(2)]-cotinine by capillary liquid chromatography-electrospray tandem mass spectrometry
A selective and sensitive LC/MS/MS assay was developed for the quantification of d(2)-nicotine and d(2)-cotinine in plasma of current and past smokers administered d(2)-nicotine. After solid phase extraction and liquid liquid extraction, HPLC separation was achieved on a capillary hydrophilic intera...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2007
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2234036/ https://ncbi.nlm.nih.gov/pubmed/17644451 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2007.06.018 |
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