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Simultaneous and Sensitive Measurement of Nicotine, Cotinine, trans-3’-Hydroxycotinine and Norcotinine in Human Plasma by Liquid Chromatography-Tandem Mass Spectrometry

An LCMSMS method for the simultaneous quantification of nicotine, cotinine, trans-3’-hydroxycotinine and norcotinine in human plasma was developed and fully validated. Potential endogenous and exogenous interferences were extensively evaluated and limits of quantification were determined by decreasi...

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Detalhes bibliográficos
Main Authors: Shakleya, Diaa M., Huestis, Marilyn A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2763023/
https://ncbi.nlm.nih.gov/pubmed/19748838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2009.08.033
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