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Simultaneous Quantification of Nicotine, Cotinine, trans-3′-Hydroxycotinine, Norcotinine and Mecamylamine in Human Urine by Liquid Chromatography-Tandem Mass Spectrometry
BACKGROUND: Mecamylamine is a nicotine antagonist under investigation in combination with nicotine replacement for smoking treatment. METHODS: A simple, rapid and reliable liquid chromatography tandem mass spectrometry (LCMSMS) method was developed and validated for quantifying nicotine, cotinine, t...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3319642/ https://ncbi.nlm.nih.gov/pubmed/22394455 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cca.2012.02.017 |
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