The Myosin SRX Comes into Focus

par Muretta, Joseph M.
Publié dans Biophys J (2020)

Mutation that causes hypertrophic cardiomyopathy increases force production in human β-cardiac myosin

par Muretta, Joseph M., Thomas, David D.
Publié 2013

Direct real-time detection of the actin-activated power stroke within the myosin catalytic domain

par Muretta, Joseph M., Petersen, Karl J., Thomas, David D.
Publié 2013

Heart failure drug changes the mechanoenzymology of the cardiac myosin powerstroke

par Rohde, John A., Thomas, David D., Muretta, Joseph M.
Publié dans Proc Natl Acad Sci U S A (2017)

Allosteric Communication in Dictyostelium Myosin II

par Guhathakurta, Piyali, Prochniewicz, Ewa, Muretta, Joseph M., Titus, Margaret A., Thomas, David D.
Publié 2012

Magnesium impacts myosin V motor activity by altering key conformational changes in the mechanochemical cycle

par Trivedi, Darshan, Muretta, Joseph M., Swenson, Anja M., Thomas, David D., Yengo, Christopher M.
Publié 2013

Direct real-time detection of the structural and biochemical events in the myosin power stroke

par Muretta, Joseph M., Rohde, John A., Johnsrud, Daniel O., Cornea, Sinziana, Thomas, David D.
Publié dans Proc Natl Acad Sci U S A (2015)

The structural kinetics of switch-1 and the neck linker explain the functions of kinesin-1 and Eg5

par Muretta, Joseph M., Jun, Yonggun, Gross, Steven P., Major, Jennifer, Thomas, David D., Rosenfeld, Steven S.
Publié dans Proc Natl Acad Sci U S A (2015)

High-performance time-resolved fluorescence by direct waveform recording

par Muretta, Joseph M., Kyrychenko, Alexander, Ladokhin, Alexey S., Kast, David J., Gillispie, Gregory D., Thomas, David D.
Publié 2010

Fluorescence lifetime plate reader: Resolution and precision meet high-throughput

par Petersen, Karl J., Peterson, Kurt C., Muretta, Joseph M., Higgins, Sutton E., Gillispie, Gregory D., Thomas, David D.
Publié dans Rev Sci Instrum (2014)

Direct measurements of the coordination of lever arm swing and the catalytic cycle in myosin V

par Trivedi, Darshan V., Muretta, Joseph M., Swenson, Anja M., Davis, Jonathon P., Thomas, David D., Yengo, Christopher M.
Publié dans Proc Natl Acad Sci U S A (2015)

A continuous fluorescence displacement assay for BioA: An enzyme involved in biotin biosynthesis

par Wilson, Daniel J., Shi, Ce, Duckworth, Benjamin P., Muretta, Joseph M., Manjunatha, Ujjini, Sham, Yuk Y., Thomas, David D., Aldrich, Courtney C.
Publié 2011

Loop L5 Assumes Three Distinct Orientations during the ATPase Cycle of the Mitotic Kinesin Eg5: A TRANSIENT AND TIME-RESOLVED FLUORESCENCE STUDY

par Muretta, Joseph M., Behnke-Parks, William M., Major, Jennifer, Petersen, Karl J., Goulet, Adeline, Moores, Carolyn A., Thomas, David D., Rosenfeld, Steven S.
Publié 2013

High-throughput spectral and lifetime-based FRET screening in living cells to identify small-molecule effectors of SERCA

par Schaaf, Tory M., Peterson, Kurt C., Grant, Benjamin D., Bawaskar, Prachi, Yuen, Samantha, Li, Ji, Muretta, Joseph M., Gillispie, Gregory D., Thomas, David D.
Publié dans SLAS Discov (2016)

Quantitative conformational profiling of kinase inhibitors reveals origins of selectivity for Aurora kinase activation states

par Lake, Eric W., Muretta, Joseph M., Thompson, Andrew R., Rasmussen, Damien M., Majumdar, Abir, Faber, Erik B., Ruff, Emily F., Thomas, David D., Levinson, Nicholas M.
Publié dans Proc Natl Acad Sci U S A (2018)

Converter domain mutations in myosin alter structural kinetics and motor function

par Gunther, Laura K., Rohde, John A., Tang, Wanjian, Walton, Shane D., Unrath, William C., Trivedi, Darshan V., Muretta, Joseph M., Thomas, David D., Yengo, Christopher M.
Publié dans J Biol Chem (2019)

The divergent mitotic kinesin MKLP2 exhibits atypical structure and mechanochemistry

par Atherton, Joseph, Yu, I-Mei, Cook, Alexander, Muretta, Joseph M, Joseph, Agnel, Major, Jennifer, Sourigues, Yannick, Clause, Jeffrey, Topf, Maya, Rosenfeld, Steven S, Houdusse, Anne, Moores, Carolyn A
Publié dans eLife (2017)

Allostery governs Cdk2 activation and differential recognition of CDK inhibitors

par Majumdar, Abir, Burban, David J., Muretta, Joseph M., Thompson, Andrew R., Engel, Tiffany A., Rasmussen, Damien M., Subrahmanian, Manu V., Veglia, Gianluigi, Thomas, David D., Levinson, Nicholas M.
Publié dans Nat Chem Biol (2021)

High-Throughput FRET Assay Yields Allosteric SERCA Activators

par Cornea, Razvan L., Lockamy, Elizabeth L., Gruber, Simon J., Muretta, Joseph M., Jin, Dongzhu, Chen, Jiqiu, Dahl, Russell, Bartfai, Tamas, Zsebo, Krisztina M., Gillispie, Gregory D., Thomas, David D.
Publié 2012

A dynamic mechanism for allosteric activation of Aurora kinase A by activation loop phosphorylation

par Ruff, Emily F, Muretta, Joseph M, Thompson, Andrew R, Lake, Eric W, Cyphers, Soreen, Albanese, Steven K, Hanson, Sonya M, Behr, Julie M, Thomas, David D, Chodera, John D, Levinson, Nicholas M
Publié dans eLife (2018)