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High-throughput spectral and lifetime-based FRET screening in living cells to identify small-molecule effectors of SERCA
A robust high-throughput screening (HTS) strategy has been developed to discover small-molecule effectors targeting the sarco/endoplasmic reticulum calcium ATPase (SERCA), based on a fluorescence microplate reader that records both the nanosecond decay waveform (lifetime mode) and the complete emiss...
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| Publicado no: | SLAS Discov |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5323330/ https://ncbi.nlm.nih.gov/pubmed/27899691 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1087057116680151 |
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