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A continuous fluorescence displacement assay for BioA: An enzyme involved in biotin biosynthesis
Cofactor biosynthetic pathways represent a rich source of potential antibiotic targets. The second step in biotin biosynthesis is performed by BioA, a pyridoxal 5′-phosphate (PLP) dependent enzyme. This enzyme has been confirmed as a candidate target in Mycobacterium tuberculosis; however, the curre...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3135573/ https://ncbi.nlm.nih.gov/pubmed/21621502 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2011.05.003 |
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