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The divergent mitotic kinesin MKLP2 exhibits atypical structure and mechanochemistry
MKLP2, a kinesin-6, has critical roles during the metaphase-anaphase transition and cytokinesis. Its motor domain contains conserved nucleotide binding motifs, but is divergent in sequence (~35% identity) and size (~40% larger) compared to other kinesins. Using cryo-electron microscopy and biophysic...
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| 出版年: | eLife |
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| 主要な著者: | , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
eLife Sciences Publications, Ltd
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5602324/ https://ncbi.nlm.nih.gov/pubmed/28826477 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.27793 |
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