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The Structural Basis of Force Generation by the Mitotic Motor Kinesin-5

Kinesin-5 is required for forming the bipolar spindle during mitosis. Its motor domain, which contains nucleotide and microtubule binding sites and mechanical elements to generate force, has evolved distinct properties for its spindle-based functions. In this study, we report subnanometer resolution...

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Hlavní autoři: Goulet, Adeline, Behnke-Parks, William M., Sindelar, Charles V., Major, Jennifer, Rosenfeld, Steven S., Moores, Carolyn A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3531780/
https://ncbi.nlm.nih.gov/pubmed/23135273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.404228
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