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Comprehensive structural model of the mechanochemical cycle of a mitotic motor highlights molecular adaptations in the kinesin family

Kinesins are responsible for a wide variety of microtubule-based, ATP-dependent functions. Their motor domain drives these activities, but the molecular adaptations that specify these diverse and essential cellular activities are poorly understood. It has been assumed that the first identified kines...

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Detalhes bibliográficos
Main Authors: Goulet, Adeline, Major, Jennifer, Jun, Yonggun, Gross, Steven P., Rosenfeld, Steven S., Moores, Carolyn A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3918802/
https://ncbi.nlm.nih.gov/pubmed/24449904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1319848111
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