Structural Dynamics of Actin during Active Interaction with Myosin Depends on the Isoform of the Essential Light Chain

Por Prochniewicz, Ewa, Guhathakurta, Piyali, Thomas, David D.
Publicado em 2013

Amplitude of the actomyosin power stroke depends strongly on the isoform of the myosin essential light chain

Por Guhathakurta, Piyali, Prochniewicz, Ewa, Thomas, David D.
Publicado no Proc Natl Acad Sci U S A (2015)

Actin-Myosin Interaction: Structure, Function and Drug Discovery

Por Guhathakurta, Piyali, Prochniewicz, Ewa, Thomas, David D.
Publicado no Int J Mol Sci (2018)

A Cardiomyopathy Mutation in the Myosin Essential Light Chain Alters Actomyosin Structure

Por Guhathakurta, Piyali, Prochniewicz, Ewa, Roopnarine, Osha, Rohde, John A., Thomas, David D.
Publicado no Biophys J (2017)

Allosteric Communication in Dictyostelium Myosin II

Por Guhathakurta, Piyali, Prochniewicz, Ewa, Muretta, Joseph M., Titus, Margaret A., Thomas, David D.
Publicado em 2012

High-throughput screen, using time-resolved FRET, yields actin-binding compounds that modulate actin–myosin structure and function

Por Guhathakurta, Piyali, Prochniewicz, Ewa, Grant, Benjamin D., Peterson, Kurt C., Thomas, David D.
Publicado no J Biol Chem (2018)

Actin-binding compounds, previously discovered by FRET-based high-throughput screening, differentially affect skeletal and cardiac muscle

Por Guhathakurta, Piyali, Phung, Lien A., Prochniewicz, Ewa, Lichtenberger, Sarah, Wilson, Anna, Thomas, David D.
Publicado no J Biol Chem (2020)

Novel drug discovery platform for spinocerebellar ataxia, using fluorescence technology targeting β-III-spectrin

Por Rebbeck, Robyn T., Andrick, Anna K., Denha, Sarah A., Svensson, Bengt, Guhathakurta, Piyali, Thomas, David D., Hays, Thomas S., Avery, Adam W.
Publicado no J Biol Chem (2020)