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Amplitude of the actomyosin power stroke depends strongly on the isoform of the myosin essential light chain

We have used time-resolved fluorescence resonance energy transfer (TR-FRET) to determine the role of myosin essential light chains (ELCs) in structural transitions within the actomyosin complex. Skeletal muscle myosins have two ELC isoforms, A1 and A2, which differ by an additional 40–45 residues at...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Guhathakurta, Piyali, Prochniewicz, Ewa, Thomas, David D.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4403186/
https://ncbi.nlm.nih.gov/pubmed/25825773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1420101112
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