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Amplitude of the actomyosin power stroke depends strongly on the isoform of the myosin essential light chain
We have used time-resolved fluorescence resonance energy transfer (TR-FRET) to determine the role of myosin essential light chains (ELCs) in structural transitions within the actomyosin complex. Skeletal muscle myosins have two ELC isoforms, A1 and A2, which differ by an additional 40–45 residues at...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4403186/ https://ncbi.nlm.nih.gov/pubmed/25825773 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1420101112 |
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