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Structural Dynamics of Actin during Active Interaction with Myosin Depends on the Isoform of the Essential Light Chain

We have used time-resolved phosphorescence anisotropy (TPA) to investigate the effects of essential light chain (ELC) isoforms (A1 and A2) on the interaction of skeletal muscle myosin with actin, in order to relate structural dynamics to previously reported functional effects. Actin was labeled with...

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Detalhes bibliográficos
Main Authors: Prochniewicz, Ewa, Guhathakurta, Piyali, Thomas, David D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3628823/
https://ncbi.nlm.nih.gov/pubmed/23339370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi3014467
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