Therapeutic Strategies for Restoring Tau Homeostasis

Tekijä Young, Zapporah T., Mok, Sue Ann, Gestwicki, Jason E.
Julkaisussa Cold Spring Harb Perspect Med (2018)

Prion-Like Propagation Mechanisms in Tauopathies and Traumatic Brain Injury: Challenges and Prospects

Tekijä Alyenbaawi, Hadeel, Allison, W. Ted, Mok, Sue-Ann
Julkaisussa Biomolecules (2020)

Deciphering Network Crosstalk: The Current Status and Potential of miRNA Regulatory Networks on the HSP40 Molecular Chaperone Network

Tekijä Budrass, Lion, Fahlman, Richard P., Mok, Sue-Ann
Julkaisussa Front Genet (2021)

Functional genomics screen identifies proteostasis targets that modulate prion protein (PrP) stability

Tekijä Abrams, Jennifer, Arhar, Taylor, Mok, Sue Ann, Taylor, Isabelle R., Kampmann, Martin, Gestwicki, Jason E.
Julkaisussa Cell Stress Chaperones (2021)

BAG3 is a modular, scaffolding protein that physically links heat shock protein 70 (Hsp70) to the small heat shock proteins

Tekijä Rauch, Jennifer N., Tse, Eric, Freilich, Rebecca, Mok, Sue-Ann, Makley, Leah N., Southworth, Daniel R., Gestwicki, Jason E.
Julkaisussa J Mol Biol (2016)

Competing protein-protein interactions regulate binding of Hsp27 to its client protein tau

Tekijä Freilich, Rebecca, Betegon, Miguel, Tse, Eric, Mok, Sue-Ann, Julien, Olivier, Agard, David A., Southworth, Daniel R., Takeuchi, Koh, Gestwicki, Jason E.
Julkaisussa Nat Commun (2018)

SIRT1 Deacetylates Tau and Reduces Pathogenic Tau Spread in a Mouse Model of Tauopathy

Tekijä Min, Sang-Won, Sohn, Peter Dongmin, Li, Yaqiao, Devidze, Nino, Johnson, Jeffrey R., Krogan, Nevan J., Masliah, Eliezer, Mok, Sue-Ann, Gestwicki, Jason E., Gan, Li
Julkaisussa J Neurosci (2018)

Promoting tau secretion and propagation by hyperactive p300/CBP via autophagy-lysosomal pathway in tauopathy

Tekijä Chen, Xu, Li, Yaqiao, Wang, Chao, Tang, Yinyan, Mok, Sue-Ann, Tsai, Richard M., Rojas, Julio C., Karydas, Anna, Miller, Bruce L., Boxer, Adam L., Gestwicki, Jason E., Arkin, Michelle, Cuervo, Ana Maria, Gan, Li
Julkaisussa Mol Neurodegener (2020)

High-Throughput Screen of Natural Product Extracts in A Yeast Model of Polyglutamine Proteotoxicity

Tekijä Walter, Gladis M., Raveh, Avi, Mok, Sue-Ann, McQuade, Thomas J., Arevang, Carl J., Schultz, Pamela J., Smith, Matthew C., Asare, Samuel, Cruz, Patricia G., Wisen, Susanne, Matainaho, Teatulohi, Sherman, David H., Gestwicki, Jason E.
Julkaistu 2014

Compromised function of the ESCRT pathway promotes endolysosomal escape of tau seeds and propagation of tau aggregation

Tekijä Chen, John J., Nathaniel, Diane L., Raghavan, Preethi, Nelson, Maxine, Tian, Ruilin, Tse, Eric, Hong, Jason Y., See, Stephanie K., Mok, Sue-Ann, Hein, Marco Y., Southworth, Daniel R., Grinberg, Lea T., Gestwicki, Jason E., Leonetti, Manuel D., Kampmann, Martin
Julkaisussa J Biol Chem (2019)

Mapping Interactions with the Chaperone Network Reveals Factors that Protect Against Tau Aggregation

Tekijä Mok, Sue-Ann, Condello, Carlo, Freilich, Rebecca, Gillies, Anne, Arhar, Taylor, Oroz, Javier, Kadavath, Harindranath, Julien, Olivier, Assimon, Victoria A., Rauch, Jennifer N., Dunyak, Bryan M., Lee, Jungsoon, Tsai, Francis T.F., Wilson, Mark R., Zweckstetter, Markus, Dickey, Chad A., Gestwicki, Jason E.
Julkaisussa Nat Struct Mol Biol (2018)

Critical Role of Acetylation in Tau-Mediated Neurodegeneration and Cognitive Deficits

Tekijä Min, Sang-Won, Chen, Xu, Tracy, Tara E, Li, Yaqiao, Zhou, Yungui, Wang, Chao, Shirakawa, Kotaro, Minami, S. Sakura, Defensor, Erwin, Mok, Sue Ann, Sohn, Peter Dongmin, Schilling, Birgit, Cong, Xin, Ellerby, Lisa, Gibson, Bradford W., Johnson, Jeffrey, Krogan, Nevan, Shamloo, Mehrdad, Gestwicki, Jason, Masliah, Eliezer, Verdin, Eric, Gan, Li
Julkaisussa Nat Med (2015)

Pathogenic Tau Impairs Axon Initial Segment Plasticity and Excitability Homeostasis

Tekijä Sohn, Peter Dongmin, Huang, Cindy Tzu-Ling, Yan, Rui, Fan, Li, Tracy, Tara E., Camargo, Carolina M., Montgomery, Kelly M., Arhar, Taylor, Mok, Sue-Ann, Freilich, Rebecca, Baik, Justin, He, Manni, Gong, Shiaoching, Roberson, Erik D., Karch, Celeste M., Gestwicki, Jason E., Xu, Ke, Kosik, Kenneth S., Gan, Li
Julkaisussa Neuron (2019)