Therapeutic Strategies for Restoring Tau Homeostasis

af Young, Zapporah T., Mok, Sue Ann, Gestwicki, Jason E.
Udgivet i Cold Spring Harb Perspect Med (2018)

Prion-Like Propagation Mechanisms in Tauopathies and Traumatic Brain Injury: Challenges and Prospects

af Alyenbaawi, Hadeel, Allison, W. Ted, Mok, Sue-Ann
Udgivet i Biomolecules (2020)

Deciphering Network Crosstalk: The Current Status and Potential of miRNA Regulatory Networks on the HSP40 Molecular Chaperone Network

af Budrass, Lion, Fahlman, Richard P., Mok, Sue-Ann
Udgivet i Front Genet (2021)

Functional genomics screen identifies proteostasis targets that modulate prion protein (PrP) stability

af Abrams, Jennifer, Arhar, Taylor, Mok, Sue Ann, Taylor, Isabelle R., Kampmann, Martin, Gestwicki, Jason E.
Udgivet i Cell Stress Chaperones (2021)

BAG3 is a modular, scaffolding protein that physically links heat shock protein 70 (Hsp70) to the small heat shock proteins

af Rauch, Jennifer N., Tse, Eric, Freilich, Rebecca, Mok, Sue-Ann, Makley, Leah N., Southworth, Daniel R., Gestwicki, Jason E.
Udgivet i J Mol Biol (2016)

Competing protein-protein interactions regulate binding of Hsp27 to its client protein tau

af Freilich, Rebecca, Betegon, Miguel, Tse, Eric, Mok, Sue-Ann, Julien, Olivier, Agard, David A., Southworth, Daniel R., Takeuchi, Koh, Gestwicki, Jason E.
Udgivet i Nat Commun (2018)

SIRT1 Deacetylates Tau and Reduces Pathogenic Tau Spread in a Mouse Model of Tauopathy

af Min, Sang-Won, Sohn, Peter Dongmin, Li, Yaqiao, Devidze, Nino, Johnson, Jeffrey R., Krogan, Nevan J., Masliah, Eliezer, Mok, Sue-Ann, Gestwicki, Jason E., Gan, Li
Udgivet i J Neurosci (2018)

Promoting tau secretion and propagation by hyperactive p300/CBP via autophagy-lysosomal pathway in tauopathy

af Chen, Xu, Li, Yaqiao, Wang, Chao, Tang, Yinyan, Mok, Sue-Ann, Tsai, Richard M., Rojas, Julio C., Karydas, Anna, Miller, Bruce L., Boxer, Adam L., Gestwicki, Jason E., Arkin, Michelle, Cuervo, Ana Maria, Gan, Li
Udgivet i Mol Neurodegener (2020)

High-Throughput Screen of Natural Product Extracts in A Yeast Model of Polyglutamine Proteotoxicity

af Walter, Gladis M., Raveh, Avi, Mok, Sue-Ann, McQuade, Thomas J., Arevang, Carl J., Schultz, Pamela J., Smith, Matthew C., Asare, Samuel, Cruz, Patricia G., Wisen, Susanne, Matainaho, Teatulohi, Sherman, David H., Gestwicki, Jason E.
Udgivet 2014

Compromised function of the ESCRT pathway promotes endolysosomal escape of tau seeds and propagation of tau aggregation

af Chen, John J., Nathaniel, Diane L., Raghavan, Preethi, Nelson, Maxine, Tian, Ruilin, Tse, Eric, Hong, Jason Y., See, Stephanie K., Mok, Sue-Ann, Hein, Marco Y., Southworth, Daniel R., Grinberg, Lea T., Gestwicki, Jason E., Leonetti, Manuel D., Kampmann, Martin
Udgivet i J Biol Chem (2019)

Mapping Interactions with the Chaperone Network Reveals Factors that Protect Against Tau Aggregation

af Mok, Sue-Ann, Condello, Carlo, Freilich, Rebecca, Gillies, Anne, Arhar, Taylor, Oroz, Javier, Kadavath, Harindranath, Julien, Olivier, Assimon, Victoria A., Rauch, Jennifer N., Dunyak, Bryan M., Lee, Jungsoon, Tsai, Francis T.F., Wilson, Mark R., Zweckstetter, Markus, Dickey, Chad A., Gestwicki, Jason E.
Udgivet i Nat Struct Mol Biol (2018)

Critical Role of Acetylation in Tau-Mediated Neurodegeneration and Cognitive Deficits

af Min, Sang-Won, Chen, Xu, Tracy, Tara E, Li, Yaqiao, Zhou, Yungui, Wang, Chao, Shirakawa, Kotaro, Minami, S. Sakura, Defensor, Erwin, Mok, Sue Ann, Sohn, Peter Dongmin, Schilling, Birgit, Cong, Xin, Ellerby, Lisa, Gibson, Bradford W., Johnson, Jeffrey, Krogan, Nevan, Shamloo, Mehrdad, Gestwicki, Jason, Masliah, Eliezer, Verdin, Eric, Gan, Li
Udgivet i Nat Med (2015)

Pathogenic Tau Impairs Axon Initial Segment Plasticity and Excitability Homeostasis

af Sohn, Peter Dongmin, Huang, Cindy Tzu-Ling, Yan, Rui, Fan, Li, Tracy, Tara E., Camargo, Carolina M., Montgomery, Kelly M., Arhar, Taylor, Mok, Sue-Ann, Freilich, Rebecca, Baik, Justin, He, Manni, Gong, Shiaoching, Roberson, Erik D., Karch, Celeste M., Gestwicki, Jason E., Xu, Ke, Kosik, Kenneth S., Gan, Li
Udgivet i Neuron (2019)