Selective Inhibitors of Protozoan Protein N-myristoyltransferases as Starting Points for Tropical Disease Medicinal Chemistry Programs

по Bell, Andrew S., Mills, James E., Williams, Gareth P., Brannigan, James A., Wilkinson, Anthony J., Parkinson, Tanya, Leatherbarrow, Robin J., Tate, Edward W., Holder, Anthony A., Smith, Deborah F.
Опубликовано 2012

Continuing analysis of microRNA origins: Formation from transposable element insertions and noncoding RNA mutations

по Roberts, Justin T, Cooper, Elvera A, Favreau, Connor J, Howell, Jacob S, Lane, Lee G, Mills, James E, Newman, Derrick C, Perry, Tabitha J, Russell, Meaghan E, Wallace, Brittany M, Borchert, Glen M
Опубликовано 2013

Discovery of a First-In-Class Small Molecule Antagonist against the Adrenomedullin-2 Receptor: Structure–Activity Relationships and Optimization

по Zirimwabagabo, Jean-Olivier, Jailani, Ameera B. A., Avgoustou, Paris, Tozer, Matthew J., Gibson, Karl R., Glossop, Paul A., Mills, James E. J., Porter, Roderick A., Blaney, Paul, Wang, Ning, Skerry, Timothy M., Richards, Gareth O., Harrity, Joseph P. A.
Опубликовано в: J Med Chem (2021)

Novel Oxindole Sulfonamides and Sulfamides: EPZ031686, the First Orally Bioavailable Small Molecule SMYD3 Inhibitor

по Mitchell, Lorna H., Boriack-Sjodin, P. Ann, Smith, Sherri, Thomenius, Michael, Rioux, Nathalie, Munchhof, Michael, Mills, James E., Klaus, Christine, Totman, Jennifer, Riera, Thomas V., Raimondi, Alejandra, Jacques, Suzanne L., West, Kip, Foley, Megan, Waters, Nigel J., Kuntz, Kevin W., Wigle, Tim J., Scott, Margaret Porter, Copeland, Robert A., Smith, Jesse J., Chesworth, Richard
Опубликовано в: ACS Med Chem Lett (2015)

Discovery of a First-in-Class Potent Small Molecule Antagonist against the Adrenomedullin-2 Receptor

по Avgoustou, Paris, Jailani, Ameera B. A., Zirimwabagabo, Jean-Olivier, Tozer, Matthew J., Gibson, Karl R., Glossop, Paul A., Mills, James E. J., Porter, Roderick A., Blaney, Paul, Bungay, Peter J., Wang, Ning, Shaw, Alice P., Bigos, Kamilla J. A., Holmes, Joseph L., Warrington, Jessica I., Skerry, Timothy M., Harrity, Joseph P. A., Richards, Gareth O.
Опубликовано в: ACS Pharmacol Transl Sci (2020)

Small molecule inhibitors and CRISPR/Cas9 mutagenesis demonstrate that SMYD2 and SMYD3 activity are dispensable for autonomous cancer cell proliferation

по Thomenius, Michael J., Totman, Jennifer, Harvey, Darren, Mitchell, Lorna H., Riera, Thomas V., Cosmopoulos, Kat, Grassian, Alexandra R., Klaus, Christine, Foley, Megan, Admirand, Elizabeth A., Jahic, Haris, Majer, Christina, Wigle, Tim, Jacques, Suzanne L., Gureasko, Jodi, Brach, Dorothy, Lingaraj, Trupti, West, Kip, Smith, Sherri, Rioux, Nathalie, Waters, Nigel J., Tang, Cuyue, Raimondi, Alejandra, Munchhof, Michael, Mills, James E., Ribich, Scott, Porter Scott, Margaret, Kuntz, Kevin W., Janzen, William P., Moyer, Mikel, Smith, Jesse J., Chesworth, Richard, Copeland, Robert A., Boriack-Sjodin, P. Ann
Опубликовано в: PLoS One (2018)