Biochemical pathways that regulate acetyltransferase and deacetylase activity in mammalian cells

por Mellert, Hestia S., McMahon, Steven B.
Publicado 2009

A Blood-based Test for the Detection of ROS1 and RET Fusion Transcripts from Circulating Ribonucleic Acid Using Digital Polymerase Chain Reaction

por Mellert, Hestia S., Alexander, Kristin E., Jackson, Leisa P., Pestano, Gary A.
Publicado en J Vis Exp (2018)

Design and Characterization of a Novel Blood Collection and Transportation Device for Proteomic Applications

por Kaiser, Nathan K., Steers, Maximillian, Nichols, Charles M., Mellert, Hestia, Pestano, Gary A.
Publicado en Diagnostics (Basel) (2020)

Targeted Next-Generation Sequencing of Liquid Biopsy Samples from Patients with NSCLC

por Mellert, Hestia, Reese, Jordan, Jackson, Leisa, Maxwell, Victoria, Tschida, Chérie, Pestano, Gary A.
Publicado en Diagnostics (Basel) (2021)

Acetylation of the p53 DNA binding domain regulates apoptosis induction.

por Sykes, Stephen M., Mellert, Hestia S., Holbert, Marc A., Li, Keqin, Marmorstein, Ronen, Lane, William S., McMahon, Steven B.
Publicado 2006

Deacetylation of the DNA-binding Domain Regulates p53-mediated Apoptosis

por Mellert, Hestia S., Stanek, Timothy J., Sykes, Stephen M., Rauscher, Frank J., Schultz, David C., McMahon, Steven B.
Publicado 2011

A rare DNA contact mutation in cancer confers p53 gain‐of‐function and tumor cell survival via TNFAIP8 induction

por Monteith, Jessica A., Mellert, Hestia, Sammons, Morgan A., Kuswanto, Laudita A., Sykes, Stephen M., Resnick-Silverman, Lois, Manfredi, James J., Berger, Shelley L., McMahon, Steven B.
Publicado en Mol Oncol (2016)

Nuclear Cyclin D1/CDK4 Kinase Regulates CUL4 Expression and Triggers Neoplastic Growth via Activation of the PRMT5 Methyltransferase

por Aggarwal, Priya, Vaites, Laura Pontano, Kim, Jong Kyong, Mellert, Hestia, Gurung, Buddha, Nakagawa, Hiroshi, Herlyn, Meenhard, Hua, Xianxin, Rustgi, Anil K., McMahon, Steven B., Diehl, J. Alan
Publicado 2010

Global analysis of p53-regulated transcription identifies its direct targets and unexpected regulatory mechanisms

por Allen, Mary Ann, Andrysik, Zdenek, Dengler, Veronica L, Mellert, Hestia S, Guarnieri, Anna, Freeman, Justin A, Sullivan, Kelly D, Galbraith, Matthew D, Luo, Xin, Kraus, W Lee, Dowell, Robin D, Espinosa, Joaquin M
Publicado 2014

Inhibition of the Single Downstream Target BAG1 Activates the Latent Apoptotic Potential of MYC

por Zhang, Xiao-Yong, Pfeiffer, Harla K., Mellert, Hestia S., Stanek, Timothy J., Sussman, Robyn T., Kumari, Alpana, Yu, Duonan, Rigoutsos, Isidore, Thomas-Tikhonenko, Andrei, Seidel, Hans E., Chodosh, Lewis A., Packham, Graham, Baserga, Renato, McMahon, Steven B.
Publicado 2011

The retinoblastoma tumor suppressor modulates DNA repair and radioresponsiveness

por Thangavel, Chellappagounder, Boopathi, Ettickan, Ciment, Steve, Liu, Yi, O’Neill, Raymond, Sharma, Ankur, McMahon, Steve B., Mellert, Hestia, Addya, Sankar, Ertel, Adam, Birbe, Ruth, Fortina, Paolo, Dicker, Adam P, Knudsen, Karen E, Den, Robert B
Publicado 2014

Phosphorylation of Tip60 by GSK-3 determines the induction of PUMA and apoptosis by p53

por Charvet, Céline, Wissler, Manuela, Brauns-Schubert, Prisca, Wang, Shang-Jui, Tang, Yi, Sigloch, Florian C., Mellert, Hestia, Brandenburg, Martin, Lindner, Silke E., Breit, Bernhard, Green, Douglas R., McMahon, Steven B., Borner, Christoph, Gu, Wei, Maurer, Ulrich
Publicado 2011

MYST protein acetyltransferase activity requires active site lysine autoacetylation

por Yuan, Hua, Rossetto, Dorine, Mellert, Hestia, Dang, Weiwei, Srinivasan, Madhusudan, Johnson, Jamel, Hodawadekar, Santosh, Ding, Emily C, Speicher, Kaye, Abshiru, Nebiyu, Perry, Rocco, Wu, Jiang, Yang, Chao, Zheng, Y George, Speicher, David W, Thibault, Pierre, Verreault, Alain, Johnson, F Bradley, Berger, Shelley L, Sternglanz, Rolf, McMahon, Steven B, Côté, Jacques, Marmorstein, Ronen
Publicado 2012

Multi-focal control of mitochondrial gene expression by oncogenic MYC provides potential therapeutic targets in cancer

por Oran, Amanda R., Adams, Clare M., Zhang, Xiao-yong, Gennaro, Victoria J., Pfeiffer, Harla K., Mellert, Hestia S., Seidel, Hans E., Mascioli, Kirsten, Kaplan, Jordan, Gaballa, Mahmoud R., Shen, Chen, Rigoutsos, Isidore, King, Michael P., Cotney, Justin L., Arnold, Jamie J., Sharma, Suresh D., Martinez, Ubaldo E., Vakoc, Christopher R., Chodosh, Lewis A., Thompson, James E., Bradner, James E., Cameron, Craig E., Shadel, Gerald S., Eischen, Christine M., McMahon, Steven B.
Publicado en Oncotarget (2016)