Nuclear Cyclin D1/CDK4 Kinase Regulates CUL4 Expression and Triggers Neoplastic Growth via Activation of the PRMT5 Methyltransferase

Cyclin D1 elicits transcriptional effects through inactivation of the retinoblastoma protein and direct association with transcriptional regulators. The current work reveals a molecular relationship between cyclin D1/CDK4 kinase and protein arginine methyltransferase 5 (PRMT5), an enzyme associated...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Aggarwal, Priya, Vaites, Laura Pontano, Kim, Jong Kyong, Mellert, Hestia, Gurung, Buddha, Nakagawa, Hiroshi, Herlyn, Meenhard, Hua, Xianxin, Rustgi, Anil K., McMahon, Steven B., Diehl, J. Alan
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2957477/
https://ncbi.nlm.nih.gov/pubmed/20951943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2010.08.012
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados