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MYST protein acetyltransferase activity requires active site lysine autoacetylation

The MYST protein lysine acetyltransferases are evolutionarily conserved throughout eukaryotes and acetylate proteins to regulate diverse biological processes including gene regulation, DNA repair, cell-cycle regulation, stem cell homeostasis and development. Here, we demonstrate that MYST protein ac...

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Detalhes bibliográficos
Principais autores: Yuan, Hua, Rossetto, Dorine, Mellert, Hestia, Dang, Weiwei, Srinivasan, Madhusudan, Johnson, Jamel, Hodawadekar, Santosh, Ding, Emily C, Speicher, Kaye, Abshiru, Nebiyu, Perry, Rocco, Wu, Jiang, Yang, Chao, Zheng, Y George, Speicher, David W, Thibault, Pierre, Verreault, Alain, Johnson, F Bradley, Berger, Shelley L, Sternglanz, Rolf, McMahon, Steven B, Côté, Jacques, Marmorstein, Ronen
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3252582/
https://ncbi.nlm.nih.gov/pubmed/22020126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.382
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