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Molecular basis for histone acetyltransferase regulation by binding partners, associated domains, and autoacetylation

Acetylation is a post-translational modification (PTM) that regulates chromatin dynamics and function. Dysregulation of acetylation or acetyltransferase activity has been correlated with several human diseases. Many, if not all histone acetyltransferases (HATs) are regulated in part through tethered...

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Detalhes bibliográficos
Publicado no:ACS Chem Biol
Main Authors: McCullough, Cheryl E., Marmorstein, Ronen
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5067162/
https://ncbi.nlm.nih.gov/pubmed/26555232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.5b00841
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