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In vitro activity assays for MYST histone acetyltransferases and adaptation for high-throughput inhibitor screening

Lysine acetylation is a post-translational modification that is carried out by acetyltransferases. The MYST proteins form the largest and most diverse family of acetyltransferases, which regulate gene expression, DNA repair, and cell cycle homeostasis, among other activities, by acetylating both his...

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Publicado en:Methods Enzymol
Main Authors: McCullough, Cheryl E., Marmorstein, Ronen
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5072368/
https://ncbi.nlm.nih.gov/pubmed/27372752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2016.01.016
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