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In vitro activity assays for MYST histone acetyltransferases and adaptation for high-throughput inhibitor screening
Lysine acetylation is a post-translational modification that is carried out by acetyltransferases. The MYST proteins form the largest and most diverse family of acetyltransferases, which regulate gene expression, DNA repair, and cell cycle homeostasis, among other activities, by acetylating both his...
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| Veröffentlicht in: | Methods Enzymol |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5072368/ https://ncbi.nlm.nih.gov/pubmed/27372752 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2016.01.016 |
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