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High throughput screening identifies modulators of histone deacetylase inhibitors

BACKGROUND: Previous studies from our laboratory and others have demonstrated that in addition to altering chromatin acetylation and conformation, histone deacetylase inhibitors (HDACi) disrupt the acetylation status of numerous transcription factors and other proteins. A whole genome yeast deletion...

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Autori principali: Gaupel, Ann-Christin, Begley, Thomas, Tenniswood, Martin
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4089024/
https://ncbi.nlm.nih.gov/pubmed/24968945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-528
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