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A high-throughput screening identifies histone deacetylase inhibitors as therapeutic agents against medulloblastoma

BACKGROUND: Medulloblastoma is the most frequently occurring malignant brain tumor in children. Current treatment strategies for medulloblastoma include aggressive surgery, cranio-spinal irradiation and adjuvant chemotherapy. Because current treatments can cause severe long-term side effects and are...

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Detalhes bibliográficos
Publicado no:Exp Hematol Oncol
Main Authors: Zhang, Shanshan, Gong, Zhaojian, Oladimeji, Peter O., Currier, Duane G., Deng, Qipan, Liu, Ming, Chen, Taosheng, Li, Yong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6858705/
https://ncbi.nlm.nih.gov/pubmed/31788346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40164-019-0153-x
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