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HIGH-THROUGHPUT DRUG SCREENING IDENTIFIES HDAC INHIBITORS AS CANDIDATE THERAPEUTICS FOR MYC-DRIVEN MEDULLOBLASTOMA
BACKGROUND: Medulloblastoma (MB) is a highly malignant pediatric brain tumor. Despite aggressive therapy, many patients succumb to the disease, and survivors experience severe side effects from treatment. MBs with high levels of the MYC oncogene have a particularly poor prognosis, and would benefit...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4144567/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou208.22 |
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