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Chaperone-mediated acetylation of histones by Rtt109 identified by quantitative proteomics

Rtt109 is a fungal-specific histone acetyltransferase (HAT) that associates with either Vps75 or Asf1 to acetylate histone H3. Recent biochemical and structural studies suggest that site-specific acetylation of H3 by Rtt109 is dictated by the binding chaperone where Rtt109-Asf1 acetylates K56, while...

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Detalhes bibliográficos
Main Authors: Abshiru, Nebiyu, Ippersiel, Kevin, Tang, Yong, Yuan, Hua, Marmorstein, Ronen, Verreault, Alain, Thibault, Pierre
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4016993/
https://ncbi.nlm.nih.gov/pubmed/23036725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jprot.2012.09.026
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