Myeloproliferative neoplasm stem cells

Por Mead, Adam J., Mullally, Ann
Publicado no Blood (2017)

Application of single-cell genomics in cancer: promise and challenges

Por Wills, Quin F., Mead, Adam J.
Publicado no Hum Mol Genet (2015)

Clinical potential of pacritinib in the treatment of myelofibrosis

Por Duenas-Perez, Ana B., Mead, Adam J.
Publicado no Ther Adv Hematol (2015)

Ruxolitinib is effective in patients with intermediate-1 risk myelofibrosis: a summary of recent evidence

Por Harrison, Claire N., Talpaz, Moshe, Mead, Adam J.
Publicado no Leuk Lymphoma (2016)

Germline Counterparts of Oncogenic Mutations: Who Gives a JAK?

Por Mead, Adam J., Constantinescu, Stefan N., Jacobsen, Sten Eirik W.
Publicado em 2013

Erythropoietin guides multipotent hematopoietic progenitor cells toward an erythroid fate

Por Grover, Amit, Mancini, Elena, Moore, Susan, Mead, Adam J., Atkinson, Deborah, Rasmussen, Kasper D., O’Carroll, Donal, Jacobsen, Sten Eirik W., Nerlov, Claus
Publicado em 2014

A dynamic niche provides Kit ligand in a stage-specific manner to the earliest thymocyte progenitors

Por Buono, Mario, Facchini, Raffaella, Matsuoka, Sahoko, Thongjuea, Supat, Waithe, Dominique, Luis, Tiago C., Giustacchini, Alice, Besmer, Peter, Mead, Adam J., Jacobsen, Sten Eirik W., Nerlov, Claus
Publicado no Nat Cell Biol (2016)

Single-cell profiling of human megakaryocyte-erythroid progenitors identifies distinct megakaryocyte and erythroid differentiation pathways

Por Psaila, Bethan, Barkas, Nikolaos, Iskander, Deena, Roy, Anindita, Anderson, Stacie, Ashley, Neil, Caputo, Valentina S., Lichtenberg, Jens, Loaiza, Sandra, Bodine, David M., Karadimitris, Anastasios, Mead, Adam J., Roberts, Irene
Publicado no Genome Biol (2016)

Mbd3/NuRD controls lymphoid cell fate and inhibits tumorigenesis by repressing a B cell transcriptional program

Por Loughran, Stephen J., Comoglio, Federico, Hamey, Fiona K., Giustacchini, Alice, Errami, Youssef, Earp, Eleanor, Göttgens, Berthold, Jacobsen, Sten Eirik W., Mead, Adam J., Hendrich, Brian, Green, Anthony R.
Publicado no J Exp Med (2017)

FLT3-ITDs Instruct a Myeloid Differentiation and Transformation Bias in Lymphomyeloid Multipotent Progenitors

Por Mead, Adam J., Kharazi, Shabnam, Atkinson, Deborah, Macaulay, Iain, Pecquet, Christian, Loughran, Stephen, Lutteropp, Michael, Woll, Petter, Chowdhury, Onima, Luc, Sidinh, Buza-Vidas, Natalija, Ferry, Helen, Clark, Sally-Ann, Goardon, Nicolas, Vyas, Paresh, Constantinescu, Stefan N., Sitnicka, Ewa, Nerlov, Claus, Jacobsen, Sten Eirik W.
Publicado em 2013

Niche-mediated depletion of the normal hematopoietic stem cell reservoir by Flt3-ITD–induced myeloproliferation

Por Mead, Adam J., Neo, Wen Hao, Barkas, Nikolaos, Matsuoka, Sahoko, Giustacchini, Alice, Facchini, Raffaella, Thongjuea, Supat, Jamieson, Lauren, Booth, Christopher A.G., Fordham, Nicholas, Di Genua, Cristina, Atkinson, Deborah, Chowdhury, Onima, Repapi, Emmanouela, Gray, Nicki, Kharazi, Shabnam, Clark, Sally-Ann, Bouriez, Tiphaine, Woll, Petter, Suda, Toshio, Nerlov, Claus, Jacobsen, Sten Eirik W.
Publicado no J Exp Med (2017)

Perturbation of fetal liver hematopoietic stem and progenitor cell development by trisomy 21

Por Roy, Anindita, Cowan, Gillian, Mead, Adam J., Filippi, Sarah, Bohn, Georg, Chaidos, Aristeidis, Tunstall, Oliver, Chan, Jerry K. Y., Choolani, Mahesh, Bennett, Phillip, Kumar, Sailesh, Atkinson, Deborah, Wyatt-Ashmead, Josephine, Hu, Ming, Stumpf, Michael P. H., Goudevenou, Katerina, O'Connor, David, Chou, Stella T., Weiss, Mitchell J., Karadimitris, Anastasios, Jacobsen, Sten Eirik, Vyas, Paresh, Roberts, Irene
Publicado em 2012

Initial seeding of embryonic thymus by immune-restricted lympho-myeloid progenitors

Por Luis, Tiago C., Luc, Sidinh, Mizukami, Takuo, Boukarabila, Hanane, Thongjuea, Supat, Woll, Petter S., Azzoni, Emanuele, Giustacchini, Alice, Lutteropp, Michael, Bouriez-Jones, Tiphaine, Vaidya, Harsh, Mead, Adam J., Atkinson, Deborah, Böiers, Charlotta, Carrelha, Joana, Macaulay, Iain C., Patient, Roger, Geissmann, Frederic, Nerlov, Claus, Sandberg, Rickard, de Bruijn, Marella F.T.R., Blackburn, C. Clare, Godin, Isabelle, Jacobsen, Sten Eirik W.
Publicado no Nat Immunol (2016)

The Earliest Thymic T Cell Progenitors Sustain B Cell and Myeloid Lineage Potentials

Por Luc, Sidinh, Luis, Tiago C., Boukarabila, Hanane, Macaulay, Iain C., Buza-Vidas, Natalija, Bouriez-Jones, Tiphaine, Lutteropp, Michael, Woll, Petter S., Loughran, Stephen J., Mead, Adam J., Hultquist, Anne, Brown, John, Mizukami, Takuo, Matsuoka, Sahoko, Ferry, Helen, Anderson, Kristina, Duarte, Sara, Atkinson, Deborah, Soneji, Shamit, Domanski, Aniela, Farley, Alison, Sanjuan-Pla, Alejandra, Carella, Cintia, Patient, Roger, de Bruijn, Marella, Enver, Tariq, Nerlov, Claus, Blackburn, Clare, Godin, Isabelle, Jacobsen, Sten Eirik W.
Publicado em 2012

Genetic variation at MECOM, TERT, JAK2 and HBS1L-MYB predisposes to myeloproliferative neoplasms

Por Tapper, William, Jones, Amy V., Kralovics, Robert, Harutyunyan, Ashot S., Zoi, Katerina, Leung, William, Godfrey, Anna L., Guglielmelli, Paola, Callaway, Alison, Ward, Daniel, Aranaz, Paula, White, Helen E., Waghorn, Katherine, Lin, Feng, Chase, Andrew, Joanna Baxter, E., Maclean, Cathy, Nangalia, Jyoti, Chen, Edwin, Evans, Paul, Short, Michael, Jack, Andrew, Wallis, Louise, Oscier, David, Duncombe, Andrew S., Schuh, Anna, Mead, Adam J., Griffiths, Michael, Ewing, Joanne, Gale, Rosemary E., Schnittger, Susanne, Haferlach, Torsten, Stegelmann, Frank, Döhner, Konstanze, Grallert, Harald, Strauch, Konstantin, Tanaka, Toshiko, Bandinelli, Stefania, Giannopoulos, Andreas, Pieri, Lisa, Mannarelli, Carmela, Gisslinger, Heinz, Barosi, Giovanni, Cazzola, Mario, Reiter, Andreas, Harrison, Claire, Campbell, Peter, Green, Anthony R., Vannucchi, Alessandro, Cross, Nicholas C.P.
Publicado no Nat Commun (2015)