Transforming Growth Factor β Drives Hemogenic Endothelium Programming and the Transition to Hematopoietic Stem Cells

Autor Monteiro, Rui, Pinheiro, Philip, Joseph, Nicola, Peterkin, Tessa, Koth, Jana, Repapi, Emmanouela, Bonkhofer, Florian, Kirmizitas, Arif, Patient, Roger
Vydáno v Dev Cell (2016)

Does osteogenic potential of clonal human bone marrow mesenchymal stem/stromal cells correlate with their vascular supportive ability?

Autor Merryweather-Clarke, Alison T., Cook, David, Lara, Barbara Joo, Hua, Peng, Repapi, Emmanouela, Ashley, Neil, Lim, Shiang Y., Watt, Suzanne M.
Vydáno v Stem Cell Res Ther (2018)

From Pioneer to Repressor: Bimodal foxd3 Activity Dynamically Remodels Neural Crest Regulatory Landscape In Vivo

Autor Lukoseviciute, Martyna, Gavriouchkina, Daria, Williams, Ruth M., Hochgreb-Hagele, Tatiana, Senanayake, Upeka, Chong-Morrison, Vanessa, Thongjuea, Supat, Repapi, Emmanouela, Mead, Adam, Sauka-Spengler, Tatjana
Vydáno v Dev Cell (2018)

Reconstruction of the Global Neural Crest Gene Regulatory Network In Vivo

Autor Williams, Ruth M., Candido-Ferreira, Ivan, Repapi, Emmanouela, Gavriouchkina, Daria, Senanayake, Upeka, Ling, Irving T.C., Telenius, Jelena, Taylor, Stephen, Hughes, Jim, Sauka-Spengler, Tatjana
Vydáno v Dev Cell (2019)

Interferon-induced transmembrane protein-3 rs12252-C is associated with rapid progression of acute HIV-1 infection in Chinese MSM cohort

Autor Zhang, Yonghong, Makvandi-Nejad, Shokouh, Qin, Ling, Zhao, Yan, Zhang, Tong, Wang, Lili, Repapi, Emmanouela, Taylor, Stephen, McMichael, Andrew, Li, Ning, Dong, Tao, Wu, Hao
Vydáno v AIDS (2015)

MLL-AF4 binds directly to a BCL-2 specific enhancer and modulates H3K27 acetylation

Autor Godfrey, Laura, Kerry, Jon, Thorne, Ross, Repapi, Emmanouela, Davies, James O.J., Tapia, Marta, Ballabio, Erica, Hughes, Jim R., Geng, Huimin, Konopleva, Marina, Milne, Thomas A.
Vydáno v Exp Hematol (2017)

BET inhibition disrupts transcription but retains enhancer-promoter contact

Autor Crump, Nicholas T., Ballabio, Erica, Godfrey, Laura, Thorne, Ross, Repapi, Emmanouela, Kerry, Jon, Tapia, Marta, Hua, Peng, Lagerholm, Christoffer, Filippakopoulos, Panagis, Davies, James O. J., Milne, Thomas A.
Vydáno v Nat Commun (2021)

IL-6 effector function of group-2 innate lymphoid cells (ILC2) is NOD2 dependent

Autor Hardman, Clare S., Chen, Yi-Ling, Salimi, Maryam, Nahler, Janina, Corridoni, Daniele, Jagielowicz, Marta, Fonseka, Chathuranga L., Johnson, David, Repapi, Emmanouela, Cousins, David J., Barlow, Jillian L., McKenzie, Andrew N. J., Simmons, Alison, Ogg, Graham
Vydáno v Sci Immunol (2021)

MLL-AF4 Spreading Identifies Binding Sites that Are Distinct from Super-Enhancers and that Govern Sensitivity to DOT1L Inhibition in Leukemia

Autor Kerry, Jon, Godfrey, Laura, Repapi, Emmanouela, Tapia, Marta, Blackledge, Neil P., Ma, Helen, Ballabio, Erica, O’Byrne, Sorcha, Ponthan, Frida, Heidenreich, Olaf, Roy, Anindita, Roberts, Irene, Konopleva, Marina, Klose, Robert J., Geng, Huimin, Milne, Thomas A.
Vydáno v Cell Rep (2017)

DOT1L inhibition reveals a distinct subset of enhancers dependent on H3K79 methylation

Autor Godfrey, Laura, Crump, Nicholas T., Thorne, Ross, Lau, I-Jun, Repapi, Emmanouela, Dimou, Dimitra, Smith, Alastair L., Harman, Joe R., Telenius, Jelena M., Oudelaar, A. Marieke, Downes, Damien J., Vyas, Paresh, Hughes, Jim R., Milne, Thomas A.
Vydáno v Nat Commun (2019)

IGF-1R inhibition induces schedule-dependent sensitization of human melanoma to temozolomide

Autor Ramcharan, Roger, Aleksic, Tamara, Kamdoum, Wilfride Petnga, Gao, Shan, Pfister, Sophia X., Tanner, Jordan, Bridges, Esther, Asher, Ruth, Watson, Amanda J., Margison, Geoffrey P., Woodcock, Mick, Repapi, Emmanouela, Li, Ji-Liang, Middleton, Mark R., Macaulay, Valentine M.
Vydáno v Oncotarget (2015)

SCL/TAL1 cooperates with Polycomb RYBP-PRC1 to suppress alternative lineages in blood-fated cells

Autor Chagraoui, Hedia, Kristiansen, Maiken S., Ruiz, Juan Pablo, Serra-Barros, Ana, Richter, Johanna, Hall-Ponselé, Elisa, Gray, Nicki, Waithe, Dominic, Clark, Kevin, Hublitz, Philip, Repapi, Emmanouela, Otto, Georg, Sopp, Paul, Taylor, Stephen, Thongjuea, Supat, Vyas, Paresh, Porcher, Catherine
Vydáno v Nat Commun (2018)

A Comprehensive Analysis of the Impact of HIV on HCV Immune Responses and Its Association with Liver Disease Progression in a Unique Plasma Donor Cohort

Autor Zhang, Yong-Hong, Zhao, Yan, Rajapaksa, Ushani S., Lawrence, Tessa M., Peng, Yan-Chun, Liu, Jinghua, Xu, Keyi, Hu, Ke, Qin, Ling, Liu, Ning, Sun, Huanqin, Yan, Hui-Ping, Repapi, Emmanouela, Rowland-Jones, Sarah, Thimme, Robert, McKeating, Jane A., Dong, Tao
Vydáno v PLoS One (2016)

Heterogeneity of human lympho-myeloid progenitors at the single cell level

Autor Karamitros, Dimitris, Stoilova, Bilyana, Aboukhalil, Zahra, Hamey, Fiona, Reinisch, Andreas, Samitsch, Marina, Quek, Lynn, Otto, Georg, Repapi, Emmanouela, Doondeea, Jessica, Usukhbayar, Batchimeg, Calvo, Julien, Taylor, Stephen, Goardon, Nicolas, Six, Emmanuelle, Pflumio, Francoise, Porcher, Catherine, Majeti, Ravindra, Gottgens, Berthold, Vyas, Paresh
Vydáno v Nat Immunol (2017)

Cell-intrinsic depletion of Aml1-ETO-expressing pre-leukemic hematopoietic stem cells by K-Ras activating mutation

Autor Di Genua, Cristina, Norfo, Ruggiero, Rodriguez-Meira, Alba, Wen, Wei Xiong, Drissen, Roy, Booth, Christopher A.G., Povinelli, Benjamin, Repapi, Emmanouela, Gray, Nicki, Carrelha, Joana, Kettyle, Laura M., Jamieson, Lauren, Neo, Wen Hao, Thongjuea, Supat, Nerlov, Claus, Mead, Adam J.
Vydáno v Haematologica (2019)

A Polymorphic p53 Response Element in KIT Ligand Influences Cancer Risk and Has Undergone Natural Selection

Autor Zeron-Medina, Jorge, Wang, Xuting, Repapi, Emmanouela, Campbell, Michelle R., Su, Dan, Castro-Giner, Francesc, Davies, Benjamin, Peterse, Elisabeth F.P., Sacilotto, Natalia, Walker, Graeme J., Terzian, Tamara, Tomlinson, Ian P., Box, Neil F., Meinshausen, Nicolai, De Val, Sarah, Bell, Douglas A., Bond, Gareth L.
Vydáno 2013

The U2AF1(S34F) mutation induces lineage-specific splicing alterations in myelodysplastic syndromes

Autor Yip, Bon Ham, Steeples, Violetta, Repapi, Emmanouela, Armstrong, Richard N., Llorian, Miriam, Roy, Swagata, Shaw, Jacqueline, Dolatshad, Hamid, Taylor, Stephen, Verma, Amit, Bartenstein, Matthias, Vyas, Paresh, Cross, Nicholas C.P., Malcovati, Luca, Cazzola, Mario, Hellström-Lindberg, Eva, Ogawa, Seishi, Smith, Christopher W.J., Pellagatti, Andrea, Boultwood, Jacqueline
Vydáno v J Clin Invest (2017)

The U2AF1(S34F) mutation induces lineage-specific splicing alterations in myelodysplastic syndromes

Autor Yip, Bon Ham, Steeples, Violetta, Repapi, Emmanouela, Armstrong, Richard N., Llorian, Miriam, Roy, Swagata, Shaw, Jacqueline, Dolatshad, Hamid, Taylor, Stephen, Verma, Amit, Bartenstein, Matthias, Vyas, Paresh, Cross, Nicholas C.P., Malcovati, Luca, Cazzola, Mario, Hellström-Lindberg, Eva, Ogawa, Seishi, Smith, Christopher W.J., Pellagatti, Andrea, Boultwood, Jacqueline
Vydáno v J Clin Invest (2017)

Transcriptomic profiling of the myeloma bone-lining niche reveals BMP signalling inhibition to improve bone disease

Autor Gooding, Sarah, Olechnowicz, Sam W. Z., Morris, Emma V., Armitage, Andrew E., Arezes, Joao, Frost, Joe, Repapi, Emmanouela, Edwards, James R., Ashley, Neil, Waugh, Craig, Gray, Nicola, Martinez-Hackert, Erik, Lim, Pei Jin, Pasricha, Sant-Rayn, Knowles, Helen, Mead, Adam J., Ramasamy, Karthik, Drakesmith, Hal, Edwards, Claire M.
Vydáno v Nat Commun (2019)

Multi-Modal Characterization of Monocytes in Idiopathic Pulmonary Fibrosis Reveals a Primed Type I Interferon Immune Phenotype

Autor Fraser, Emily, Denney, Laura, Antanaviciute, Agne, Blirando, Karl, Vuppusetty, Chaitanya, Zheng, Yuejuan, Repapi, Emmanouela, Iotchkova, Valentina, Taylor, Stephen, Ashley, Neil, St Noble, Victoria, Benamore, Rachel, Hoyles, Rachel, Clelland, Colin, Rastrick, Joseph M. D., Hardman, Clare S., Alham, Nasullah K., Rigby, Rachel E., Simmons, Alison, Rehwinkel, Jan, Ho, Ling-Pei
Vydáno v Front Immunol (2021)