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Transforming Growth Factor β Drives Hemogenic Endothelium Programming and the Transition to Hematopoietic Stem Cells

Hematopoietic stem cells (HSCs) are self-renewing multipotent stem cells that generate mature blood lineages throughout life. They, together with hematopoietic progenitor cells (collectively known as HSPCs), emerge from hemogenic endothelium in the floor of the embryonic dorsal aorta by an endotheli...

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Bibliografiske detaljer
Udgivet i:Dev Cell
Main Authors: Monteiro, Rui, Pinheiro, Philip, Joseph, Nicola, Peterkin, Tessa, Koth, Jana, Repapi, Emmanouela, Bonkhofer, Florian, Kirmizitas, Arif, Patient, Roger
Format: Artigo
Sprog:Inglês
Udgivet: Cell Press 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4998007/
https://ncbi.nlm.nih.gov/pubmed/27499523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2016.06.024
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