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Activation of Arterial Program Drives Development of Definitive Hemogenic Endothelium with Lymphoid Potential

Understanding pathways guiding the development of definitive hematopoiesis with lymphoid potential is essential for advancing human pluripotent stem cell (hPSC) technologies for treatment of blood diseases and immunotherapies. In the embryo, lymphoid progenitors and hematopoietic stem cells (HSCs) a...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Rep
Prif Awduron: Park, Mi Ae, Kumar, Akhilesh, Jung, Ho Sun, Uenishi, Gene, Moskvin, Oleg V., Thomson, James A., Slukvin, Igor I.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6410360/
https://ncbi.nlm.nih.gov/pubmed/29791856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.04.092
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