Activation of Arterial Program Drives Development of Definitive Hemogenic Endothelium with Lymphoid Potential

Understanding pathways guiding the development of definitive hematopoiesis with lymphoid potential is essential for advancing human pluripotent stem cell (hPSC) technologies for treatment of blood diseases and immunotherapies. In the embryo, lymphoid progenitors and hematopoietic stem cells (HSCs) a...

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Gepubliceerd in:Cell Rep
Hoofdauteurs: Park, Mi Ae, Kumar, Akhilesh, Jung, Ho Sun, Uenishi, Gene, Moskvin, Oleg V., Thomson, James A., Slukvin, Igor I.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6410360/
https://ncbi.nlm.nih.gov/pubmed/29791856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.04.092
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