NOTCH signaling specifies arterial-type definitive hemogenic endothelium from human pluripotent stem cells

NOTCH signaling is required for the arterial specification and formation of hematopoietic stem cells (HSCs) and lympho-myeloid progenitors in the embryonic aorta-gonad-mesonephros region and extraembryonic vasculature from a distinct lineage of vascular endothelial cells with hemogenic potential. Ho...

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Publicado no:Nat Commun
Main Authors: Uenishi, Gene I., Jung, Ho Sun, Kumar, Akhilesh, Park, Mi Ae, Hadland, Brandon K., McLeod, Ethan, Raymond, Matthew, Moskvin, Oleg, Zimmerman, Catherine E., Theisen, Derek J., Swanson, Scott, J. Tamplin, Owen, Zon, Leonard I., Thomson, James A., Bernstein, Irwin D., Slukvin, Igor I.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5940870/
https://ncbi.nlm.nih.gov/pubmed/29739946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04134-7
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