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GATA2 Is Dispensable for Specification of Hemogenic Endothelium but Promotes Endothelial-to-Hematopoietic Transition

The transcriptional factor GATA2 is required for blood and hematopoietic stem cell formation during the hemogenic endothelium (HE) stage of development in the embryo. However, it is unclear if GATA2 controls HE lineage specification or if it solely regulates endothelial-to-hematopoietic transition (...

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Bibliographic Details
Published in:Stem Cell Reports
Main Authors: Kang, HyunJun, Mesquitta, Walatta-Tseyon, Jung, Ho Sun, Moskvin, Oleg V., Thomson, James A., Slukvin, Igor I.
Format: Artigo
Language:Inglês
Published: Elsevier 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6066910/
https://ncbi.nlm.nih.gov/pubmed/29861167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2018.05.002
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