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GATA2 Is Dispensable for Specification of Hemogenic Endothelium but Promotes Endothelial-to-Hematopoietic Transition

The transcriptional factor GATA2 is required for blood and hematopoietic stem cell formation during the hemogenic endothelium (HE) stage of development in the embryo. However, it is unclear if GATA2 controls HE lineage specification or if it solely regulates endothelial-to-hematopoietic transition (...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Stem Cell Reports
Egile Nagusiak: Kang, HyunJun, Mesquitta, Walatta-Tseyon, Jung, Ho Sun, Moskvin, Oleg V., Thomson, James A., Slukvin, Igor I.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Elsevier 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6066910/
https://ncbi.nlm.nih.gov/pubmed/29861167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2018.05.002
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