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Activation of Arterial Program Drives Development of Definitive Hemogenic Endothelium with Lymphoid Potential

Understanding pathways guiding the development of definitive hematopoiesis with lymphoid potential is essential for advancing human pluripotent stem cell (hPSC) technologies for treatment of blood diseases and immunotherapies. In the embryo, lymphoid progenitors and hematopoietic stem cells (HSCs) a...

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Detalles Bibliográficos
Publicado en:Cell Rep
Autores principales: Park, Mi Ae, Kumar, Akhilesh, Jung, Ho Sun, Uenishi, Gene, Moskvin, Oleg V., Thomson, James A., Slukvin, Igor I.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6410360/
https://ncbi.nlm.nih.gov/pubmed/29791856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.04.092
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