Activation of Arterial Program Drives Development of Definitive Hemogenic Endothelium with Lymphoid Potential

Understanding pathways guiding the development of definitive hematopoiesis with lymphoid potential is essential for advancing human pluripotent stem cell (hPSC) technologies for treatment of blood diseases and immunotherapies. In the embryo, lymphoid progenitors and hematopoietic stem cells (HSCs) a...

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Bibliographic Details
Published in:Cell Rep
Main Authors: Park, Mi Ae, Kumar, Akhilesh, Jung, Ho Sun, Uenishi, Gene, Moskvin, Oleg V., Thomson, James A., Slukvin, Igor I.
Format: Artigo
Language:Inglês
Published: 2018
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6410360/
https://ncbi.nlm.nih.gov/pubmed/29791856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.04.092
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