Serum response factor is crucial for actin cytoskeletal organization and focal adhesion assembly in embryonic stem cells

Por Schratt, Gerhard, Philippar, Ulrike, Berger, Jürgen, Schwarz, Heinz, Heidenreich, Olaf, Nordheim, Alfred
Publicado em 2002

A Drosophila model identifies calpains as modulators of the human leukemogenic fusion protein AML1-ETO

Por Osman, Dani, Gobert, Vanessa, Ponthan, Frida, Heidenreich, Olaf, Haenlin, Marc, Waltzer, Lucas
Publicado em 2009

Determination of key structure–activity relationships in siRNA delivery with a mixed micelle system()()

Por Omedes Pujol, Marta, Coleman, Daniel J.L., Allen, Christopher D., Heidenreich, Olaf, Fulton, David A.
Publicado em 2013

AML1/ETO proteins control POU4F1/BRN3A expression and function in t(8;21) acute myeloid leukaemia

Por Dunne, Jenny, Gascoyne, Duncan M., Lister, T. Andrew, Brady, Hugh J.M., Heidenreich, Olaf, Young, Bryan D.
Publicado em 2010

siRNAs targeting the ERK2 signaling pathway and AML1/MTG8 fusion gene attenuate the differentiation, proliferation and growth arrest in t(8;21) leukemia

Por Bashanfer, Salem, Al-Hassan, Faisal Mutee, Hassan, Rosline, Heidenreich, Olaf, Mohamed Said, Mohamed Saifulaman, Mohd Yusoff, Narazah
Publicado em 2012

Inhibition of adhesion molecule expression on human venous endothelial cells by non-viral siRNA transfection

Por Walker, Tobias, Wendel, Hans P, Tetzloff, Liane, Raabe, Claudia, Heidenreich, Olaf, Simon, Perikles, Scheule, Albertus M, Ziemer, Gerhard
Publicado em 2006

Inhibition of adhesion molecule expression on human venous endothelial cells by non-viral siRNA transfection

Por Walker, Tobias, Wendel, Hans P, Tetzloff, Liane, Raabe, Claudia, Heidenreich, Olaf, Simon, Perikles, Scheule, Albertus M, Ziemer, Gerhard
Publicado no J Cell Mol Med (2007)

The oncogenic fusion protein RUNX1-CBFA2T1 supports proliferation and inhibits senescence in t(8;21)-positive leukaemic cells

Por Martinez, Natalia, Drescher, Bettina, Riehle, Heidemarie, Cullmann, Claire, Vornlocher, Hans-Peter, Ganser, Arnold, Heil, Gerhard, Nordheim, Alfred, Krauter, Jürgen, Heidenreich, Olaf
Publicado em 2004

Stable depletion of RUNX1-ETO in Kasumi-1 cells induces expression and enhanced proteolytic activity of Cathepsin G and Neutrophil Elastase

Por Schoenherr, Caroline, Wohlan, Katharina, Dallmann, Iris, Pich, Andreas, Hegermann, Jan, Ganser, Arnold, Hilfiker-Kleiner, Denise, Heidenreich, Olaf, Scherr, Michaela, Eder, Matthias
Publicado no PLoS One (2019)

Acute B lymphoblastic leukaemia-propagating cells are present at high frequency in diverse lymphoblast populations

Por Rehe, Klaus, Wilson, Kerrie, Bomken, Simon, Williamson, Daniel, Irving, Julie, den Boer, Monique L, Stanulla, Martin, Schrappe, Martin, Hall, Andrew G, Heidenreich, Olaf, Vormoor, Josef
Publicado em 2013

RUNX1-ETO and RUNX1-EVI1 Differentially Reprogram the Chromatin Landscape in t(8;21) and t(3;21) AML

Por Loke, Justin, Assi, Salam A., Imperato, Maria Rosaria, Ptasinska, Anetta, Cauchy, Pierre, Grabovska, Yura, Soria, Natalia Martinez, Raghavan, Manoj, Delwel, H. Ruud, Cockerill, Peter N., Heidenreich, Olaf, Bonifer, Constanze
Publicado no Cell Rep (2017)

Development of a Preclinical Orthotopic Xenograft Model of Ewing Sarcoma and Other Human Malignant Bone Disease Using Advanced In Vivo Imaging

Por Vormoor, Britta, Knizia, Henrike K., Batey, Michael A., Almeida, Gilberto S., Wilson, Ian, Dildey, Petra, Sharma, Abhishek, Blair, Helen, Hide, I. Geoff, Heidenreich, Olaf, Vormoor, Josef, Maxwell, Ross J., Bacon, Chris M.
Publicado em 2014

Optimized induction of mitochondrial apoptosis for chemotherapy-free treatment of BCR-ABL+acute lymphoblastic leukemia

Por Scherr, Michaela, Kirchhoff, Hanna, Battmer, Karin, Wohlan, Katharina, Lee, Chun-Wei, Ricke-Hoch, Melanie, Erschow, Sergej, Law, Edward, Kloos, Arnold, Heuser, Michael, Ganser, Arnold, Hilfiker-Kleiner, Denise, Heidenreich, Olaf, Eder, Matthias
Publicado no Leukemia (2018)

MLL-AF4 Spreading Identifies Binding Sites that Are Distinct from Super-Enhancers and that Govern Sensitivity to DOT1L Inhibition in Leukemia

Por Kerry, Jon, Godfrey, Laura, Repapi, Emmanouela, Tapia, Marta, Blackledge, Neil P., Ma, Helen, Ballabio, Erica, O’Byrne, Sorcha, Ponthan, Frida, Heidenreich, Olaf, Roy, Anindita, Roberts, Irene, Konopleva, Marina, Klose, Robert J., Geng, Huimin, Milne, Thomas A.
Publicado no Cell Rep (2017)

UBASH3B/Sts-1-CBL axis regulates myeloid proliferation in human preleukemia induced by AML1-ETO

Por Goyama, Susumu, Schibler, Janet, Gasilina, Anjelika, Shrestha, Mahesh, Lin, Shan, Link, Kevin A., Chen, Jianjun, Whitman, Susan P., Bloomfield, Clara D., Nicolet, Deedra, Assi, Salam, Ptasinska, Anetta, Heidenreich, Olaf, Bonifer, Constanze, Kitamura, Toshio, Nassar, Nicolas N., Mulloy, James C.
Publicado no Leukemia (2015)

Identification of a Dynamic Core Transcriptional Network in t(8;21) AML that Regulates Differentiation Block and Self-Renewal

Por Ptasinska, Anetta, Assi, Salam A., Martinez-Soria, Natalia, Imperato, Maria Rosaria, Piper, Jason, Cauchy, Pierre, Pickin, Anna, James, Sally R., Hoogenkamp, Maarten, Williamson, Dan, Wu, Mengchu, Tenen, Daniel G., Ott, Sascha, Westhead, David R., Cockerill, Peter N., Heidenreich, Olaf, Bonifer, Constanze
Publicado no Cell Rep (2014)

Dynamic clonal progression in xenografts of acute lymphoblastic leukemia with intrachromosomal amplification of chromosome 21

Por Sinclair, Paul. B., Blair, Helen H., Ryan, Sarra L., Buechler, Lars, Cheng, Joanna, Clayton, Jake, Hanna, Rebecca, Hollern, Shaun, Hawking, Zoe, Bashton, Matthew, Schwab, Claire J., Jones, Lisa, Russell, Lisa J., Marr, Helen, Carey, Peter, Halsey, Christina, Heidenreich, Olaf, Moorman, Anthony V., Harrison, Christine J.
Publicado no Haematologica (2018)

Inhibition of ATR acutely sensitizes acute myeloid leukemia cells to nucleoside analogs that target ribonucleotide reductase

Por Fordham, Sarah E., Blair, Helen J., Elstob, Claire J., Plummer, Ruth, Drew, Yvette, Curtin, Nicola J., Heidenreich, Olaf, Pal, Deepali, Jamieson, David, Park, Catherine, Pollard, John, Fields, Scott, Milne, Paul, Jackson, Graham H., Marr, Helen J., Menne, Tobias, Jones, Gail L., Allan, James M.
Publicado no Blood Adv (2018)

Targeting the thioredoxin system as a novel strategy against B‐cell acute lymphoblastic leukemia

Por Fidyt, Klaudyna, Pastorczak, Agata, Goral, Agnieszka, Szczygiel, Kacper, Fendler, Wojciech, Muchowicz, Angelika, Bartlomiejczyk, Marcin Adam, Madzio, Joanna, Cyran, Julia, Graczyk‐Jarzynka, Agnieszka, Jansen, Eugene, Patkowska, Elzbieta, Lech‐Maranda, Ewa, Pal, Deepali, Blair, Helen, Burdzinska, Anna, Pedzisz, Piotr, Glodkowska‐Mrowka, Eliza, Demkow, Urszula, Gawle‐Krawczyk, Karolina, Matysiak, Michal, Winiarska, Magdalena, Juszczynski, Przemyslaw, Mlynarski, Wojciech, Heidenreich, Olaf, Golab, Jakub, Firczuk, Malgorzata
Publicado no Mol Oncol (2019)

Subtype-specific regulatory network rewiring in acute myeloid leukemia

Por Assi, Salam A., Imperato, Maria Rosaria, Coleman, Daniel J. L., Pickin, Anna, Potluri, Sandeep, Ptasinska, Anetta, Chin, Paulynn Suyin, Blair, Helen, Cauchy, Pierre, James, Sally R., Zacarias-Cabeza, Joaquin, Gilding, L. Niall, Beggs, Andrew, Clokie, Sam, Loke, Justin C., Jenkin, Phil, Uddin, Ash, Delwel, Ruud, Richards, Stephen J., Raghavan, Manoj, Griffiths, Michael J., Heidenreich, Olaf, Cockerill, Peter N., Bonifer, Constanze
Publicado no Nat Genet (2018)