RUNX1-ETO and RUNX1-EVI1 Differentially Reprogram the Chromatin Landscape in t(8;21) and t(3;21) AML

Acute myeloid leukemia (AML) is a heterogeneous disease caused by mutations in transcriptional regulator genes, but how different mutant regulators shape the chromatin landscape is unclear. Here, we compared the transcriptional networks of two types of AML with chromosomal translocations of the RUNX...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Rep
Prif Awduron: Loke, Justin, Assi, Salam A., Imperato, Maria Rosaria, Ptasinska, Anetta, Cauchy, Pierre, Grabovska, Yura, Soria, Natalia Martinez, Raghavan, Manoj, Delwel, H. Ruud, Cockerill, Peter N., Heidenreich, Olaf, Bonifer, Constanze
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Cell Press 2017
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5457485/
https://ncbi.nlm.nih.gov/pubmed/28538183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.05.005
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